Mebanazin
(Preusmjereno sa stranice HHRZAEJMHSGZNP-UHFFFAOYSA-N)
Mebanazin (Actomol) je inhibitor monoaminske oksidaze (MAOI) iz hidrazinske hemijske klase, koji je ranije korišten kao antidepresiv tokom 1960-tih, ali je njegova primena prekinuta.[5][6][7]
(IUPAC) ime | |||
---|---|---|---|
1-feniletilhidrazin | |||
Klinički podaci | |||
Identifikatori | |||
CAS broj | 65-64-5 | ||
ATC kod | nije dodeljen | ||
PubChem[1][2] | 6179 | ||
ChemSpider[3] | 5944 | ||
UNII | Z5R55CJ4CG | ||
ChEMBL[4] | CHEMBL1909283 | ||
Hemijski podaci | |||
Formula | C8H12N2 | ||
Mol. masa | 136,19 g/mol | ||
SMILES | eMolekuli & PubHem | ||
| |||
Farmakoinformacioni podaci | |||
Trudnoća | ? | ||
Pravni status | ℞ Prescription only | ||
Način primene | Oralno |
Reference uredi
- ↑ Li Q, Cheng T, Wang Y, Bryant SH (2010). „PubChem as a public resource for drug discovery.”. Drug Discov Today 15 (23-24): 1052-7. DOI:10.1016/j.drudis.2010.10.003. PMID 20970519.
- ↑ Evan E. Bolton, Yanli Wang, Paul A. Thiessen, Stephen H. Bryant (2008). „Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities”. Annual Reports in Computational Chemistry 4: 217-241. DOI:10.1016/S1574-1400(08)00012-1.
- ↑ Hettne KM, Williams AJ, van Mulligen EM, Kleinjans J, Tkachenko V, Kors JA. (2010). „Automatic vs. manual curation of a multi-source chemical dictionary: the impact on text mining”. J Cheminform 2 (1): 3. DOI:10.1186/1758-2946-2-3. PMID 20331846.
- ↑ Gaulton A, Bellis LJ, Bento AP, Chambers J, Davies M, Hersey A, Light Y, McGlinchey S, Michalovich D, Al-Lazikani B, Overington JP. (2012). „ChEMBL: a large-scale bioactivity database for drug discovery”. Nucleic Acids Res 40 (Database issue): D1100-7. DOI:10.1093/nar/gkr777. PMID 21948594.
- ↑ Gilmour SJ (September 1965). „Clinical trial of mebanazine--a new monoamine oxidase inhibitor”. The British Journal of Psychiatry : the Journal of Mental Science 111 (478): 899–902. PMID 5889715.
- ↑ Barker JC, Jan IA, Enoch MD (November 1965). „A controlled trial of mebanazine ('Actomol') in depression”. The British Journal of Psychiatry : the Journal of Mental Science 111 (480): 1095–100. PMID 5320546.
- ↑ Knott F (1965). „A preliminary trial of mebanazine in depressive states”. The Journal of New Drugs 5 (6): 345–7. PMID 5327282. Arhivirano iz originala na datum 2019-12-15. Pristupljeno 2014-04-05.