SRT1460

(Preusmjereno sa stranice SBEWVVLMFLTQFE-UHFFFAOYSA-N)

SRT1460 je organsko jedinjenje, koje sadrži 26 atoma ugljenika i ima molekulsku masu od 507,605 Da.

SRT1460

Klinički podaci

AHFS/Drugs.com

Identifikatori

nije dodeljen

Hemijski podaci

C₂₆H₂₉N₅O₄S

507,605

eMolekuli & PubHem

InChI
InChI=1S/C26H29N5O4S/c1-33-22-12-17(13-23(34-2)24(22)35-3)25(32)28-20-7-5-4-6-19(20)21-15-31-18(16-36-26(31)29-21)14-30-10-8-27-9-11-30/h4-7,12-13,15-16,27H,8-11,14H2,1-3H3,(H,28,32) Key: SBEWVVLMFLTQFE-UHFFFAOYSA-N^Y

Farmakoinformacioni podaci

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Osobine uredi

Osobina	Vrednost
Broj akceptora vodonika	7
Broj donora vodonika	2
Broj rotacionih veza	8
Particioni koeficijent^[2] (ALogP)	2,7
Rastvorljivost^[3] (logS, log(mol/L))	-5,5
Polarna površina^[4] (PSA, Å²)	117,6

Reference uredi

↑ Hettne KM, Williams AJ, van Mulligen EM, Kleinjans J, Tkachenko V, Kors JA. (2010). „Automatic vs. manual curation of a multi-source chemical dictionary: the impact on text mining”. J Cheminform 2 (1): 3. DOI:10.1186/1758-2946-2-3. PMID 20331846. edit
↑ Ghose, A.K., Viswanadhan V.N., and Wendoloski, J.J. (1998). „Prediction of Hydrophobic (Lipophilic) Properties of Small Organic Molecules Using Fragment Methods: An Analysis of AlogP and CLogP Methods”. J. Phys. Chem. A 102: 3762-3772. DOI:10.1021/jp980230o.
↑ Tetko IV, Tanchuk VY, Kasheva TN, Villa AE. (2001). „Estimation of Aqueous Solubility of Chemical Compounds Using E-State Indices”. Chem Inf. Comput. Sci. 41: 1488-1493. DOI:10.1021/ci000392t. PMID 11749573.
↑ Ertl P., Rohde B., Selzer P. (2000). „Fast calculation of molecular polar surface area as a sum of fragment based contributions and its application to the prediction of drug transport properties”. J. Med. Chem. 43: 3714-3717. DOI:10.1021/jm000942e. PMID 11020286.

Literatura uredi

Hardman JG, Limbird LE, Gilman AG. (2001). Goodman & Gilman's The Pharmacological Basis of Therapeutics (10 izd.). New York: McGraw-Hill. DOI:10.1036/0071422803. ISBN 0-07-135469-7.
Thomas L. Lemke, David A. Williams, ur. (2007). Foye's Principles of Medicinal Chemistry (6 izd.). Baltimore: Lippincott Willams & Wilkins. ISBN 0-7817-6879-9.

Spoljašnje veze uredi

	Portal Medicina
	Portal Hemija

SRT1460 na Wikimedijinoj ostavi

SRT1460

Izvor: https://sh.wikipedia.org/w/index.php?title=SRT1460&oldid=33594602