RHC80267 je inhibitor diacilglicerol lipaze[4]. Diacilglicerol lipaza generiše endokanabinoid 2-arahidonoilglicerol iz diacilglicerola.
| RHC80267
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| IUPAC ime
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| (cikloheksilideneamino)N-[6-[(cikloheksilidenamino)oksikarbonilamino]heksil]karbamat |
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| Drugi nazivi
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RHC 80267, RG 80267, U 57908
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| Identifikacija
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| CAS registarski broj
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83654-05-1
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| PubChem[1][2]
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5063
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| ChemSpider[3]
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4887  Y
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| MeSH
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1,6-bis(cyclohexyloximinocarbonyl)hexane
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| Jmol-3D slike
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Slika 1
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C1CCC(=NOC(=O)NCCCCCCNC(=O)ON=C2CCCCC2)CC1 |
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InChI=1S/C20H34N4O4/c25-19(27-23-17-11-5-3-6-12-17)21-15-9-1-2-10-16-22-20(26)28-24-18-13-7-4-8-14-18/h1-16H2,(H,21,25)(H,22,26) Y
Kod: RXSVYGIGWRDVQC-UHFFFAOYSA-N Y |
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| Svojstva
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| Molekulska formula
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C20H34N4O4
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| Molarna masa
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394,26
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|
 Y (šta je ovo?)
(verifikuj)
Ukoliko nije drugačije napomenuto, podaci se odnose na standardno stanje (25 °C, 100 kPa) materijala
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| Infobox references
|
- ↑ Li Q, Cheng T, Wang Y, Bryant SH (2010). „PubChem as a public resource for drug discovery.”. Drug Discov Today 15 (23-24): 1052-7. DOI:10.1016/j.drudis.2010.10.003. PMID 20970519. edit
- ↑ Evan E. Bolton, Yanli Wang, Paul A. Thiessen, Stephen H. Bryant (2008). „Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities”. Annual Reports in Computational Chemistry 4: 217-241. DOI:10.1016/S1574-1400(08)00012-1.
- ↑ Hettne KM, Williams AJ, van Mulligen EM, Kleinjans J, Tkachenko V, Kors JA. (2010). „Automatic vs. manual curation of a multi-source chemical dictionary: the impact on text mining”. J Cheminform 2 (1): 3. DOI:10.1186/1758-2946-2-3. PMID 20331846. edit
- ↑ Sutherland CA, Amin D (1982). „Relative activities of rat and dog platelet phospholipase A2 and diglyceride lipase. Selective inhibition of diglyceride lipase by RHC 80267”. J. Biol. Chem. 257 (23): 14006–10. PMID 7142192.
