Karbaminska kiselina

Karbaminska kiselina
Structural formula of carbamic acid	Ball-and-stick model of carbamic acid
	Carbamic acid
Identifikacija
CAS registarski broj	463-77-4
PubChem	277
ChemSpider	271
DrugBank	DB04261
KEGG	C01563
MeSH	Carbamic+acid
ChEBI	28616
ChEMBL	CHEMBL125278
Jmol-3D slike	Slika 1
SMILES
	O=C(O)N
InChI
	InChI=1S/CH3NO2/c2-1(3)4/h2H2,(H,3,4) ; Kod: KXDHJXZQYSOELW-UHFFFAOYSA-N InChI=1/CH3NO2/c2-1(3)4/h2H2,(H,3,4); Kod: KXDHJXZQYSOELW-UHFFFAOYAC
Svojstva
Molekulska formula	CH3NO2
Molarna masa	61.040 g/mol
Srodna jedinjenja
Srodna jedinjenja	Ditiokarbamat; Ugljena kiselina; Ureja; Etil karbamat
	(šta je ovo?) (verifikuj) ; Ukoliko nije drugačije napomenuto, podaci se odnose na standardno stanje (25 °C, 100 kPa) materijala
	Infobox references

Karbaminska kiselina je jedinjenje koje je nestabilno pod normalnim uslovima. Ona je tehnički najjednostavnija aminokiselina, mada njena nestabilnost (i jedinstvena priroda karboksil-azotne veze) omogućavaju glicinu do poprimi taj status. Na osnovu njenog imena se formiraju imena većih analoga. ^[6] Sama karbaminska kiselina nije bila sintetisana.^[7]

Radical se zove karbamoil. Karbamoiltransferaze su transferazni enzimi klasifikovan pod EC brojen 2.1.3.

karbaminska kiselinska grupa
karbamatna grupa
karbamoilna grupa

Karbaminske kiseline su intermedijari u razlaganju karbamatnih zaštitnih grupa; hidroliza estarske veze proizvodi karbaminsku kiselinu, iz koje se izdvaja ugljen dioksid, čime nastaje nezaštićeni amin.

Reference

↑ Li Q, Cheng T, Wang Y, Bryant SH (2010). „PubChem as a public resource for drug discovery.”. Drug Discov Today 15 (23-24): 1052-7. DOI:10.1016/j.drudis.2010.10.003. PMID 20970519. edit
↑ Evan E. Bolton, Yanli Wang, Paul A. Thiessen, Stephen H. Bryant (2008). „Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities”. Annual Reports in Computational Chemistry 4: 217-241. DOI:10.1016/S1574-1400(08)00012-1.
↑ Hettne KM, Williams AJ, van Mulligen EM, Kleinjans J, Tkachenko V, Kors JA. (2010). „Automatic vs. manual curation of a multi-source chemical dictionary: the impact on text mining”. J Cheminform 2 (1): 3. DOI:10.1186/1758-2946-2-3. PMID 20331846. edit
↑ Joanne Wixon, Douglas Kell (2000). „Website Review: The Kyoto Encyclopedia of Genes and Genomes — KEGG”. Yeast 17 (1): 48–55. DOI:10.1002/(SICI)1097-0061(200004)17:1<48::AID-YEA2>3.0.CO;2-H.
↑ Gaulton A, Bellis LJ, Bento AP, Chambers J, Davies M, Hersey A, Light Y, McGlinchey S, Michalovich D, Al-Lazikani B, Overington JP. (2012). „ChEMBL: a large-scale bioactivity database for drug discovery”. Nucleic Acids Res 40 (Database issue): D1100-7. DOI:10.1093/nar/gkr777. PMID 21948594. edit
↑ Thomas L. Lemke. (2003). Review of organic functional groups : introduction to medicinal organic chemistry. Philadelphia, Pa.: Lippincott Williams & Wilkins. str. 63. ISBN 9780781743815.
↑ R.K. Khanna, M.H. Moore. (1998). „A 55”. Carbamic acid: molecular structure and IR spectra (pii: S1386-1425(98)00228-5). Greenbelt, MD.: Elsevier. str. 961–967.

Literatura

Thomas L. Lemke. (2003). Review of organic functional groups : introduction to medicinal organic chemistry. Philadelphia, Pa.: Lippincott Williams & Wilkins. str. 63. ISBN 9780781743815.
R.K. Khanna, M.H. Moore. (1998). „A 55”. Carbamic acid: molecular structure and IR spectra (pii: S1386-1425(98)00228-5). Greenbelt, MD.: Elsevier. str. 961–967.

Spoljašnje veze

Portal Hemija

[1] Li Q, Cheng T, Wang Y, Bryant SH (2010). „PubChem as a public resource for drug discovery.”. Drug Discov Today 15 (23-24): 1052-7. DOI:10.1016/j.drudis.2010.10.003. PMID 20970519. edit

[2] Evan E. Bolton, Yanli Wang, Paul A. Thiessen, Stephen H. Bryant (2008). „Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities”. Annual Reports in Computational Chemistry 4: 217-241. DOI:10.1016/S1574-1400(08)00012-1.

[3] Hettne KM, Williams AJ, van Mulligen EM, Kleinjans J, Tkachenko V, Kors JA. (2010). „Automatic vs. manual curation of a multi-source chemical dictionary: the impact on text mining”. J Cheminform 2 (1): 3. DOI:10.1186/1758-2946-2-3. PMID 20331846. edit

[4] Joanne Wixon, Douglas Kell (2000). „Website Review: The Kyoto Encyclopedia of Genes and Genomes — KEGG”. Yeast 17 (1): 48–55. DOI:10.1002/(SICI)1097-0061(200004)17:1<48::AID-YEA2>3.0.CO;2-H.

[5] Gaulton A, Bellis LJ, Bento AP, Chambers J, Davies M, Hersey A, Light Y, McGlinchey S, Michalovich D, Al-Lazikani B, Overington JP. (2012). „ChEMBL: a large-scale bioactivity database for drug discovery”. Nucleic Acids Res 40 (Database issue): D1100-7. DOI:10.1093/nar/gkr777. PMID 21948594. edit

[6] Thomas L. Lemke. (2003). Review of organic functional groups : introduction to medicinal organic chemistry. Philadelphia, Pa.: Lippincott Williams & Wilkins. str. 63. ISBN 9780781743815.

[7] R.K. Khanna, M.H. Moore. (1998). „A 55”. Carbamic acid: molecular structure and IR spectra (pii: S1386-1425(98)00228-5). Greenbelt, MD.: Elsevier. str. 961–967.

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