Imidapril
(Preusmjereno sa stranice KLZWOWYOHUKJIG-BPUTZDHNSA-N)
Imidapril je ACE inhibitor koji se koristi kao antihipertenzivni lek za tretman hroničnog zatajenja srca.[6]
| |||
| (IUPAC) ime | |||
|---|---|---|---|
| (4S)-3-[(2S)-2- {[(2S)-1-etoksi-1-okso-4-fenilbutan-2-il]amino}propanoil]-1-metil-2-oksoimidazolidin-4-karboksilna kiselina | |||
| Klinički podaci | |||
| AHFS/Drugs.com | Internacionalno ime leka | ||
| Identifikatori | |||
| CAS broj | 89371-37-9 | ||
| ATC kod | C09AA16 | ||
| PubChem[1][2] | 5464343 | ||
| ChemSpider[3] | 4576628 | ||
| UNII | BW7H1TJS22 
| ||
| KEGG[4] | D08068
| ||
| ChEMBL[5] | CHEMBL317094
| ||
| Hemijski podaci | |||
| Formula | C20H27N3O6 | ||
| Mol. masa | 405,444 g/mol | ||
| SMILES | eMolekuli & PubHem | ||
| |||
| Farmakoinformacioni podaci | |||
| Trudnoća | ? | ||
| Pravni status | |||
Reference
uredi- ↑ Li Q, Cheng T, Wang Y, Bryant SH (2010). „PubChem as a public resource for drug discovery.”. Drug Discov Today 15 (23-24): 1052-7. DOI:10.1016/j.drudis.2010.10.003. PMID 20970519.
- ↑ Evan E. Bolton, Yanli Wang, Paul A. Thiessen, Stephen H. Bryant (2008). „Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities”. Annual Reports in Computational Chemistry 4: 217-241. DOI:10.1016/S1574-1400(08)00012-1.
- ↑ Hettne KM, Williams AJ, van Mulligen EM, Kleinjans J, Tkachenko V, Kors JA. (2010). „Automatic vs. manual curation of a multi-source chemical dictionary: the impact on text mining”. J Cheminform 2 (1): 3. DOI:10.1186/1758-2946-2-3. PMID 20331846.
- ↑ Joanne Wixon, Douglas Kell (2000). „Website Review: The Kyoto Encyclopedia of Genes and Genomes — KEGG”. Yeast 17 (1): 48–55. DOI:10.1002/(SICI)1097-0061(200004)17:1<48::AID-YEA2>3.0.CO;2-H.
- ↑ Gaulton A, Bellis LJ, Bento AP, Chambers J, Davies M, Hersey A, Light Y, McGlinchey S, Michalovich D, Al-Lazikani B, Overington JP. (2012). „ChEMBL: a large-scale bioactivity database for drug discovery”. Nucleic Acids Res 40 (Database issue): D1100-7. DOI:10.1093/nar/gkr777. PMID 21948594.
- ↑ Robinson, D. M.; Curran, M. P.; Lyseng-Williamson, K. A. (2007). „Imidapril: A review of its use in essential hypertension, Type 1 diabetic nephropathy and chronic heart failure”. Drugs 67 (9): 1359–1378. PMID 17547476.