Acetilpropionilmorfin

(Preusmjereno sa stranice JDTRGWXTYWXUHP-AFOIZWJHSA-N)

Acetilpropionilmorfin je organsko jedinjenje, koje sadrži 22 atoma ugljenika i ima molekulsku masu od 383,438 Da.

Acetilpropionilmorfin

Klinički podaci

AHFS/Drugs.com

Identifikatori

nije dodeljen

Hemijski podaci

C₂₂H₂₅N O₅

383,438

eMolekuli & PubHem

InChI
InChI=1S/C22H25NO5/c1-4-18(25)27-17-8-6-14-15-11-13-5-7-16(26-12(2)24)20-19(13)22(14,21(17)28-20)9-10-23(15)3/h5-8,14-15,17,21H,4,9-11H2,1-3H3/t14-,15+,17-,21-,22+/m0/s1 Key: JDTRGWXTYWXUHP-AFOIZWJHSA-N^Y

Farmakoinformacioni podaci

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Osobine uredi

Osobina	Vrednost
Broj akceptora vodonika	6
Broj donora vodonika	0
Broj rotacionih veza	5
Particioni koeficijent^[2] (ALogP)	2,5
Rastvorljivost^[3] (logS, log(mol/L))	-3,8
Polarna površina^[4] (PSA, Å²)	65,1

Reference uredi

↑ Hettne KM, Williams AJ, van Mulligen EM, Kleinjans J, Tkachenko V, Kors JA. (2010). „Automatic vs. manual curation of a multi-source chemical dictionary: the impact on text mining”. J Cheminform 2 (1): 3. DOI:10.1186/1758-2946-2-3. PMID 20331846. edit
↑ Ghose, A.K., Viswanadhan V.N., and Wendoloski, J.J. (1998). „Prediction of Hydrophobic (Lipophilic) Properties of Small Organic Molecules Using Fragment Methods: An Analysis of AlogP and CLogP Methods”. J. Phys. Chem. A 102: 3762-3772. DOI:10.1021/jp980230o.
↑ Tetko IV, Tanchuk VY, Kasheva TN, Villa AE. (2001). „Estimation of Aqueous Solubility of Chemical Compounds Using E-State Indices”. Chem Inf. Comput. Sci. 41: 1488-1493. DOI:10.1021/ci000392t. PMID 11749573.
↑ Ertl P., Rohde B., Selzer P. (2000). „Fast calculation of molecular polar surface area as a sum of fragment based contributions and its application to the prediction of drug transport properties”. J. Med. Chem. 43: 3714-3717. DOI:10.1021/jm000942e. PMID 11020286.

Literatura uredi

Hardman JG, Limbird LE, Gilman AG. (2001). Goodman & Gilman's The Pharmacological Basis of Therapeutics (10 izd.). New York: McGraw-Hill. DOI:10.1036/0071422803. ISBN 0-07-135469-7.
Thomas L. Lemke, David A. Williams, ur. (2007). Foye's Principles of Medicinal Chemistry (6 izd.). Baltimore: Lippincott Willams & Wilkins. ISBN 0-7817-6879-9.

Spoljašnje veze uredi

	Portal Medicina
	Portal Hemija

Acetilpropionilmorfin na Wikimedijinoj ostavi

Acetylpropionylmorphine

Izvor: https://sh.wikipedia.org/w/index.php?title=Acetilpropionilmorfin&oldid=33584315