Etil protokatehuat
Etil protokatehuat je fenolno jedinjenje. On je prisutan u kikirikiju.[6][7] On se isto tako javlja u vinu.[8] On je Etanolni estar protokatehuinske kiseline.
Etil protokatehuat[1] | |||
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IUPAC ime |
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Drugi nazivi | Etil estar 3,4-dihidroksibenzojeve kiselina EDHB Etil-3,4-dihidroksibenzoat | ||
Identifikacija | |||
CAS registarski broj | 3943-89-3 | ||
PubChem[2][3] | 77547 | ||
ChemSpider[4] | 69954 | ||
EINECS broj | |||
Jmol-3D slike | Slika 1 | ||
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Svojstva | |||
Molekulska formula | C9H10O4 | ||
Molarna masa | 182,17 g/mol | ||
Agregatno stanje | beli ili bledo smeđe žuti, kristalni prah; bez mirisa ili sa slabim mirisom sličnim fenolu | ||
Tačka topljenja |
132-135 °C | ||
Tačka ključanja |
357-358 °C[5] | ||
Rastvorljivost u vodi | Nerastvoran u vodi; rastvoran u etanolu | ||
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Infobox references |
Ovo jedinjenje je inhibitor prolil 4-hidroksilaze[9] i može se koristiti za zaštitu miokarda.[10]
Reference uredi
- ↑ Ethyl protocatechuate on FAO website[mrtav link]
- ↑ Li Q, Cheng T, Wang Y, Bryant SH (2010). „PubChem as a public resource for drug discovery.”. Drug Discov Today 15 (23-24): 1052-7. DOI:10.1016/j.drudis.2010.10.003. PMID 20970519.
- ↑ Evan E. Bolton, Yanli Wang, Paul A. Thiessen, Stephen H. Bryant (2008). „Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities”. Annual Reports in Computational Chemistry 4: 217-241. DOI:10.1016/S1574-1400(08)00012-1.
- ↑ Hettne KM, Williams AJ, van Mulligen EM, Kleinjans J, Tkachenko V, Kors JA. (2010). „Automatic vs. manual curation of a multi-source chemical dictionary: the impact on text mining”. J Cheminform 2 (1): 3. DOI:10.1186/1758-2946-2-3. PMID 20331846.
- ↑ Ethyl protocatechuate on www.thegoodscentscompany.com
- ↑ Huang, S. C.; Yen, G. C.; Chang, L. W.; Yen, W. J.; Duh, P. D. (2003). „Identification of an Antioxidant, Ethyl Protocatechuate, in Peanut Seed Testa”. Journal of Agricultural and Food Chemistry 51 (8): 2380–2383. DOI:10.1021/jf0210019. PMID 12670184.
- ↑ Yen, W. J.; Chang, L. W.; Duh, P. D. (2005). „Antioxidant activity of peanut seed testa and its antioxidative component, ethyl protocatechuate”. LWT - Food Science and Technology 38 (3): 193. DOI:10.1016/j.lwt.2004.06.004.
- ↑ Baderschneider, B.; Winterhalter, P. (2001). „Isolation and Characterization of Novel Benzoates, Cinnamates, Flavonoids, and Lignans from Riesling Wine and Screening for Antioxidant Activity”. Journal of Agricultural and Food Chemistry 49 (6): 2788–2798. DOI:10.1021/jf010396d. PMID 11409967.
- ↑ Wang, J.; Buss, J. L.; Chen, G.; Ponka, P.; Pantopoulos, K. (2002). „The prolyl 4-hydroxylase inhibitor ethyl-3,4-dihydroxybenzoate generates effective iron deficiency in cultured cells”. FEBS Letters 529 (2–3): 309–312. DOI:10.1016/S0014-5793(02)03389-6. PMID 12372619.
- ↑ Philipp, S.; Cui, L.; Ludolph, B.; Kelm, M.; Schulz, R.; Cohen, M. V.; Downey, J. M. (2005). „Desferoxamine and ethyl-3,4-dihydroxybenzoate protect myocardium by activating NOS and generating mitochondrial ROS”. AJP: Heart and Circulatory Physiology 290 (1): H450–H457. DOI:10.1152/ajpheart.00472.2005. PMID 16155105.