Befunolol je beta blokator sa intrinsičnom simpatomimetičkom aktivnošću koji se koristi u tretmanu glaukoma.[6]
Befunolol
|
| (IUPAC) ime
|
| (RS)-17-[2-hidroksi-3-(propan-2-ilamino)propoksi]- 1-benzofuran-2-il}etanon
|
| Klinički podaci
|
| Robne marke
|
Benfuran, Bentos, Betaclar, Glauconex
|
| AHFS/Drugs.com
|
Internacionalno ime leka
|
| Identifikatori
|
| CAS broj
|
39552-01-7
|
| ATC kod
|
S01ED06
|
| PubChem[1][2]
|
2309
|
| ChemSpider[3]
|
2219
|
| UNII
|
418546MT3A  Y
|
| KEGG[4]
|
D07496 Y
|
| ChEMBL[5]
|
CHEMBL153984 Y
|
| Hemijski podaci
|
| Formula
|
C16H21NO4
|
| Mol. masa
|
291,342 g/mol
|
| SMILES
|
eMolekuli & PubHem
|
| InChI |
|---|
InChI=1S/C16H21NO4/c1-10(2)17-8-13(19)9-20-14-6-4-5-12-7-15(11(3)18)21-16(12)14/h4-7,10,13,17,19H,8-9H2,1-3H3 Y
Key: ZPQPDBIHYCBNIG-UHFFFAOYSA-N Y |
|
| Farmakoinformacioni podaci
|
| Trudnoća
|
?
|
| Pravni status
|
|
- ↑ Li Q, Cheng T, Wang Y, Bryant SH (2010). „PubChem as a public resource for drug discovery.”. Drug Discov Today 15 (23-24): 1052-7. DOI:10.1016/j.drudis.2010.10.003. PMID 20970519. edit
- ↑ Evan E. Bolton, Yanli Wang, Paul A. Thiessen, Stephen H. Bryant (2008). „Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities”. Annual Reports in Computational Chemistry 4: 217-241. DOI:10.1016/S1574-1400(08)00012-1.
- ↑ Hettne KM, Williams AJ, van Mulligen EM, Kleinjans J, Tkachenko V, Kors JA. (2010). „Automatic vs. manual curation of a multi-source chemical dictionary: the impact on text mining”. J Cheminform 2 (1): 3. DOI:10.1186/1758-2946-2-3. PMID 20331846. edit
- ↑ Joanne Wixon, Douglas Kell (2000). „Website Review: The Kyoto Encyclopedia of Genes and Genomes — KEGG”. Yeast 17 (1): 48–55. DOI:10.1002/(SICI)1097-0061(200004)17:1<48::AID-YEA2>3.0.CO;2-H.
- ↑ Gaulton A, Bellis LJ, Bento AP, Chambers J, Davies M, Hersey A, Light Y, McGlinchey S, Michalovich D, Al-Lazikani B, Overington JP. (2012). „ChEMBL: a large-scale bioactivity database for drug discovery”. Nucleic Acids Res 40 (Database issue): D1100-7. DOI:10.1093/nar/gkr777. PMID 21948594. edit
- ↑ Stephan Reichl, Christel C Müller-Goymann (2003-02-01). „The use of a porcine organotypic cornea construct for permeation studies from formulations containing befunolol hydrochloride”. International Journal of Pharmaceutics 250 (1): 191–201.
Spoljašnje veze
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