Aldehid dehidrogenaza (pirolohinolin-hinon)
Aldehid dehidrogenaza (pirolohinolin-hinon) (EC 1.2.99.3, aldehidna dehidrogenaza (akceptor)) je enzim sa sistematskim imenom aldehid:(pirolohinolin-hinon) oksidoreduktaza.[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Aldehid dehidrogenaza (pirolohinolin-hinon) | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 1.2.99.3 | ||||||||
| CAS broj | 75536-77-5 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- aldehid + akceptor + H2O karboksilat + redukovani akceptor
Ovaj enzim je hinoprotein. On ima široku specifičnost. Deluje na pravolančane aldehide sa do C10, aromatične aldehide, glioksilat i gliceraldehid.
Reference uredi
- ↑ Ameyama, M. and Adachi, O. (1982). „Aldehyde dehydrogenase from acetic acid bacteria, membrane-bound”. Methods Enzymol. 89: 491-497.
- ↑ Ameyama, M., Osada, K., Shinagawa, E., Matsushita, K. and Adachi, O. (1981). „Purification and characterization of aldehyde dehydrogenase of Acetobacter aceti”. Agric. Biol. Chem. 45: 1189-1890.
- ↑ Patel, R.N., Hou, C.T. (1980). „, Derelanko,P. and Felix, A. Purification and properties of a heme-containing aldehyde dehydrogenase from Methylosinus trichosporium”. Arch. Biochem. Biophys. 203: 654-662. PMID 6779711.
Literatura uredi
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.