Abanohil je antagonist α1-adrenergičkog receptora.[5]
Abanohil
|
| (IUPAC) ime
|
|---|
| 2-(6,7-dimetoksi-3,4-dihidro-1H-izohinolin-2-il)-6,7-dimetoksihinolin-4-amin
|
| Klinički podaci
|
|---|
| Identifikatori
|
|---|
| CAS broj
|
90402-40-7
|
| ATC kod
|
nije dodeljen
|
| PubChem[1][2] |
164089
|
| ChemSpider[3] |
143896
|
| UNII
|
F738MWY53L  Y |
|---|
| ChEMBL[4] |
CHEMBL324090 Y |
|---|
| Hemijski podaci
|
|---|
| Formula
|
C22H25N3O4 |
| Mol. masa
|
395,452 g/mol
|
| SMILES
|
eMolekuli & PubHem
|
| InChI |
|---|
InChI=1S/C22H25N3O4/c1-26-18-7-13-5-6-25(12-14(13)8-19(18)27-2)22-10-16(23)15-9-20(28-3)21(29-4)11-17(15)24-22/h7-11H,5-6,12H2,1-4H3,(H2,23,24) Y
Key: ANZIISNSHPKVRV-UHFFFAOYSA-N Y |
|
| Farmakoinformacioni podaci
|
|---|
| Trudnoća
|
?
|
| Pravni status
|
|
- ↑ Li Q, Cheng T, Wang Y, Bryant SH (2010). „PubChem as a public resource for drug discovery.”. Drug Discov Today 15 (23-24): 1052-7. DOI:10.1016/j.drudis.2010.10.003. PMID 20970519. edit
- ↑ Evan E. Bolton, Yanli Wang, Paul A. Thiessen, Stephen H. Bryant (2008). „Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities”. Annual Reports in Computational Chemistry 4: 217-241. DOI:10.1016/S1574-1400(08)00012-1.
- ↑ Hettne KM, Williams AJ, van Mulligen EM, Kleinjans J, Tkachenko V, Kors JA. (2010). „Automatic vs. manual curation of a multi-source chemical dictionary: the impact on text mining”. J Cheminform 2 (1): 3. DOI:10.1186/1758-2946-2-3. PMID 20331846. edit
- ↑ Gaulton A, Bellis LJ, Bento AP, Chambers J, Davies M, Hersey A, Light Y, McGlinchey S, Michalovich D, Al-Lazikani B, Overington JP. (2012). „ChEMBL: a large-scale bioactivity database for drug discovery”. Nucleic Acids Res 40 (Database issue): D1100-7. DOI:10.1093/nar/gkr777. PMID 21948594. edit
- ↑ Tham, TC; Guy, S; Shanks, RG; Harron, DW (1992). „Dose-dependent alpha 1-adrenoceptor antagonist activity of the anti-arrhythmic drug, abanoquil (UK-52,046), without reduction in blood pressure in man”. British Journal of Clinical Pharmacology 33 (4): 405–9. PMC 1381330. PMID 1349492.
