Abanohil je antagonist α1-adrenergičkog receptora.[5]

Abanohil
(IUPAC) ime
2-(6,7-dimetoksi-3,4-dihidro-1H-izohinolin-2-il)-6,7-dimetoksihinolin-4-amin
Klinički podaci
Identifikatori
CAS broj 90402-40-7
ATC kod nije dodeljen
PubChem[1][2] 164089
ChemSpider[3] 143896
UNII F738MWY53L YesY
ChEMBL[4] CHEMBL324090 YesY
Hemijski podaci
Formula C22H25N3O4 
Mol. masa 395,452 g/mol
SMILES eMolekuli & PubHem
Farmakoinformacioni podaci
Trudnoća ?
Pravni status

ReferenceUredi

  1. Li Q, Cheng T, Wang Y, Bryant SH (2010). "PubChem as a public resource for drug discovery.". Drug Discov Today 15 (23-24): 1052-7. DOI:10.1016/j.drudis.2010.10.003. PMID 20970519. http://www.sciencedirect.com/science/article/pii/S1359644610007737.  edit
  2. Evan E. Bolton, Yanli Wang, Paul A. Thiessen, Stephen H. Bryant (2008). "Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities". Annual Reports in Computational Chemistry 4: 217-241. DOI:10.1016/S1574-1400(08)00012-1. 
  3. Hettne KM, Williams AJ, van Mulligen EM, Kleinjans J, Tkachenko V, Kors JA. (2010). "Automatic vs. manual curation of a multi-source chemical dictionary: the impact on text mining". J Cheminform 2 (1): 3. DOI:10.1186/1758-2946-2-3. PMID 20331846. http://www.jcheminf.com/content/2/1/3.  edit
  4. Gaulton A, Bellis LJ, Bento AP, Chambers J, Davies M, Hersey A, Light Y, McGlinchey S, Michalovich D, Al-Lazikani B, Overington JP. (2012). "ChEMBL: a large-scale bioactivity database for drug discovery". Nucleic Acids Res 40 (Database issue): D1100-7. DOI:10.1093/nar/gkr777. PMID 21948594.  edit
  5. Tham, TC; Guy, S; Shanks, RG; Harron, DW (1992). "Dose-dependent alpha 1-adrenoceptor antagonist activity of the anti-arrhythmic drug, abanoquil (UK-52,046), without reduction in blood pressure in man". British Journal of Clinical Pharmacology 33 (4): 405–9. PMC 1381330. PMID 1349492. //www.ncbi.nlm.nih.gov/pmc/articles/PMC1381330/. 

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