Prokineticinski receptor 1

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Prokineticinski receptor 1, ranije poznat kao PKR₁, je ljudski protein kodiran PROKR1 genom.

Prokineticinski receptor 1
Identifikatori
Simboli	PROKR1; PKR1; GPR73; GPR73a; ZAQ
Vanjski ID	OMIM: 607122 MGI: 1929676 HomoloGene: 10968 IUPHAR: PKR1 GeneCards: PROKR1 Gene
Ontologija gena Molekularna funkcija • rodopsinu-slična receptorska aktivnost • receptorska aktivnost • neuropeptid Y receptorska aktivnost Celularna komponenta • membrana • integralno sa membranom Biološki proces • prenos signala • signalni put G-protein spregnutog receptora
Pregled RNK izražavanja
podaci
Ortolozi
Vrsta	Čovek	Miš
Entrez	10887	58182
Ensembl	ENSG00000169618	ENSMUSG00000049409
UniProt	Q8TCW9	Q3U0M4
RefSeq (mRNA)	NM_138964	NM_021381
RefSeq (protein)	NP_620414	NP_067356
Lokacija (UCSC)	Chr 2: 68.73 - 68.74 Mb	Chr 6: 87.54 - 87.56 Mb
PubMed pretraga	[1]	[2]

Vidi još

• Prokineticinski receptor

Literatura

• Parker R, Liu M, Eyre HJ, et al. (2000). „Y-receptor-like genes GPR72 and GPR73: molecular cloning, genomic organisation and assignment to human chromosome 11q21.1 and 2p14 and mouse chromosome 9 and 6.”. Biochim. Biophys. Acta 1491 (1-3): 369–75. PMID 10760605. 
• Lin DC, Bullock CM, Ehlert FJ, et al. (2002). „Identification and molecular characterization of two closely related G protein-coupled receptors activated by prokineticins/endocrine gland vascular endothelial growth factor.”. J. Biol. Chem. 277 (22): 19276–80. DOI:10.1074/jbc.M202139200. PMID 11886876. 
• Masuda Y, Takatsu Y, Terao Y, et al. (2002). „Isolation and identification of EG-VEGF/prokineticins as cognate ligands for two orphan G-protein-coupled receptors.”. Biochem. Biophys. Res. Commun. 293 (1): 396–402. DOI:10.1016/S0006-291X(02)00239-5. PMID 12054613. 
• Soga T, Matsumoto S, Oda T, et al. (2003). „Molecular cloning and characterization of prokineticin receptors.”. Biochim. Biophys. Acta 1579 (2-3): 173–9. PMID 12427552. 
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). „Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.”. Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. DOI:10.1073/pnas.242603899. PMC 139241. PMID 12477932. 
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). „Complete sequencing and characterization of 21,243 full-length human cDNAs.”. Nat. Genet. 36 (1): 40–5. DOI:10.1038/ng1285. PMID 14702039. 
• Battersby S, Critchley HO, Morgan K, et al. (2004). „Expression and regulation of the prokineticins (endocrine gland-derived vascular endothelial growth factor and Bv8) and their receptors in the human endometrium across the menstrual cycle.”. J. Clin. Endocrinol. Metab. 89 (5): 2463–9. DOI:10.1210/jc.2003-032012. PMID 15126578. 
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). „The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).”. Genome Res. 14 (10B): 2121–7. DOI:10.1101/gr.2596504. PMC 528928. PMID 15489334. 
• Hillier LW, Graves TA, Fulton RS, et al. (2005). „Generation and annotation of the DNA sequences of human chromosomes 2 and 4.”. Nature 434 (7034): 724–31. DOI:10.1038/nature03466. PMID 15815621. 
• Pasquali D, Rossi V, Staibano S, et al. (2006). „The endocrine-gland-derived vascular endothelial growth factor (EG-VEGF)/prokineticin 1 and 2 and receptor expression in human prostate: Up-regulation of EG-VEGF/prokineticin 1 with malignancy.”. Endocrinology 147 (9): 4245–51. DOI:10.1210/en.2006-0614. PMID 16763065. 
• „Prokineticin Receptors: PKR₁”. IUPHAR Database of Receptors and Ion Channels. International Union of Basic and Clinical Pharmacology. Arhivirano iz originala na datum 2009-07-17.