Prokineticinski receptor
Prokineticinski receptor je G-protein spregnuti receptor koji vezuje peptidni hormon prokineticin.[1] Postoje dve varijante ovog peptida. One su kodirane genima: PROKR1 i PROKR2.[2] Ti receptori posreduju kontrakciju gastrointestinal glatkih mišića i angiogenezu.
| Prokineticinski receptor 1 | |
|---|---|
| Identifikatori | |
| Simbol | PROKR1 |
| Alt. simboli | GPR73 |
| Entrez | 10887 |
| HUGO | 4524 |
| OMIM | 607122 |
| RefSeq | NM_138964 |
| UniProt | Q8TCW9 |
| Drugi podaci | |
| Lokus | Hromozom 2 p14 |
| Prokineticinski receptor 2 | |
|---|---|
| Identifikatori | |
| Simbol | PROKR2 |
| Alt. simboli | GPR73L1 |
| Entrez | 128674 |
| HUGO | 15836 |
| OMIM | 607123 |
| RefSeq | NM_144773 |
| UniProt | Q8NFJ6 |
| Drugi podaci | |
| Lokus | Hromozom 20 p12.3 |
Literatura uredi
- ↑ „Prokineticin Receptors”. IUPHAR Database of Receptors and Ion Channels. International Union of Basic and Clinical Pharmacology. Arhivirano iz originala na datum 2011-05-16.
- ↑ Lin DC, Bullock CM, Ehlert FJ, Chen JL, Tian H, Zhou QY (2002). „Identification and molecular characterization of two closely related G protein-coupled receptors activated by prokineticins/endocrine gland vascular endothelial growth factor”. J. Biol. Chem. 277 (22): 19276–80. DOI:10.1074/jbc.M202139200. PMID 11886876.