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Receptor sličan D2 receptoru

Receptori slični D2 receptorima su potfamilija dopaminskih receptora koji vezuju endogeni neurotransmiter dopamin. D2-slična potfamilija se sastoji od dva G protein spregnuta receptora koji su spregnuti sa Gi/Go i posreduju inhibitornu neurotransmisiju. Ona obuhvata D1[1][2][3], D1[4][5] i D4 receptor.[6][7]

Vidi još uredi

Reference uredi

  1. ↑ Duan J, Wainwright MS, Comeron JM, Saitou N, Sanders AR, Gelernter J, Gejman PV (February 2003). „Synonymous mutations in the human dopamine receptor D2 (DRD2) affect mRNA stability and synthesis of the receptor”. Hum. Mol. Genet. 12 (3): 205–16. DOI:10.1093/hmg/ddg055. PMID 12554675. 
  2. ↑ Arinami T, Gao M, Hamaguchi H, Toru M (April 1997). „A functional polymorphism in the promoter region of the dopamine D2 receptor gene is associated with schizophrenia”. Hum. Mol. Genet. 6 (4): 577–82. DOI:10.1093/hmg/6.4.577. PMID 9097961. 
  3. ↑ Glatt SJ, Stephen Faraone, Tsuang MT (July 2004). „DRD2 -141C insertion/deletion polymorphism is not associated with schizophrenia: results of a meta-analysis”. Am. J. Med. Genet. B Neuropsychiatr. Genet. 128B (1): 21–3. DOI:10.1002/ajmg.b.30007. PMID 15211624. 
  4. ↑ Le Coniat M, Sokoloff P, Hillion J, Martres MP, Giros B, Pilon C, Schwartz JC, Berger R (Oct 1991). „Chromosomal localization of the human D3 dopamine receptor gene”. Hum Genet 87 (5): 618–20. PMID 1916765. 
  5. ↑ „Entrez Gene: DRD3 dopamine receptor D3”. 
  6. ↑ Van Tol HH, Bunzow JR, Guan HC, Sunahara RK, Seeman P, Niznik HB, Civelli O (April 1991). „Cloning of the gene for a human dopamine D4 receptor with high affinity for the antipsychotic clozapine”. Nature 350 (6319): 610–4. DOI:10.1038/350610a0. PMID 1840645. 
  7. ↑ Neve KA, Seamans JK, Trantham-Davidson H (August 2004). „Dopamine receptor signaling”. J. Recept. Signal Transduct. Res. 24 (3): 165–205. DOI:10.1081/RRS-200029981. PMID 15521361. 
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