Pirol-2-karboksilatna dekarboksilaza
Pirol-2-karboksilatna dekarboksilaza (EC 4.1.1.93) je enzim sa sistematskim imenom pirol-2-karboksilat karboksilijaza.[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Pirol-2-karboksilatna dekarboksilaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 4.1.1.93 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- (1) pirol-2-karboksilat pirol + CO2
- (2) pirol-2-karboksilat + H2O pirol + HCO3-
Ovaj enzim katalizuje reakcije karboksilacije i dekarboksilacije.
Reference uredi
- ↑ Wieser, M., Fujii, N., Yoshida, T. and Nagasawa, T. (1998). „Carbon dioxide fixation by reversible pyrrole-2-carboxylate decarboxylase from Bacillus megaterium PYR2910”. Eur. J. Biochem. 257: 495-499. PMID 9826198.
- ↑ Omura, H., Wieser, M. and Nagasawa, T. (1998). „Pyrrole-2-carboxylate decarboxylase from Bacillus megaterium PYR2910, an organic-acid-requiring enzyme”. Eur. J. Biochem. 253: 480-484. PMID 9654100.
- ↑ Wieser, M., Yoshida, T. and Nagasawa, T. (1998). „Microbial synthesis of pyrrole-2-carboxylate by Bacillus megaterium PYR2910”. Tetrahedron Lett. 39: 4309-4310.
Literatura uredi
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.