Peptid-triptofan 2,3-dioksigenaza
Peptid-triptofan 2,3-dioksigenaza (EC 1.13.11.26, pirolooksigenaza, peptidiltriptofan 2,3-dioksigenaza, triptofanska pirolooksigenaza) je enzim sa sistematskim imenom (protein)-L-triptofan:kiseonik 2,3-oksidoreduktaza (deciklizacija).[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Peptid-triptofan 2,3-dioksigenaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 1.13.11.26 | ||||||||
| CAS broj | 37256-64-7 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- [protein]-L-triptofan + O2 [protein]-N-formil-L-kinurenin
On takođe deluje na triptofan.
Reference uredi
- ↑ Frydman, R.B., Tomaro, M.L. and Frydman, B. (1972). „Pyrrolooxygenase: its action on tryptophan-containing enzymes and peptides”. Biochim. Biophys. Acta 284: 80-89. PMID 4403729.
- ↑ Camoretti-Mercado, B. and Frydman, R.B. (1986). „Separation of tryptophan pyrrolooxygenase into three molecular forms. A study of their substrate specificities using tryptophyl-containing peptides and proteins”. Eur. J. Biochem. 156: 317-325. PMID 3699018.
Literatura uredi
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.