L-serin-fosfatidiletanolamin fosfatidiltransferaza
(Preusmjereno sa stranice PTDSS2 (gene name))
L-serin-fosfatidiletanolamin fosfatidiltransferaza (EC 2.7.8.29, fosfatidilserinska sintaza 2, enzim II razmene serina, PTDSS2 (gen)) je enzim sa sistematskim imenom L-1-fosfatidiletanolamin:L-serin fosfatidiltransferaza.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
| L-serin-fosfatidiletanolamin fosfatidiltransferaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 2.7.8.29 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- L-1-fosfatidiletanolamin + L-serin L-1-fosfatidilserin + etanolamin
Enzim sisara katalizuje reakciju razmene u kojoj se polarna čeona grupa fosfatidiletanolamina zamenjuje L-serinom.
Reference
uredi- ↑ Stone, S.J. and Vance, J.E. (1999). „Cloning and expression of murine liver phosphatidylserine synthase (PSS)-2: differential regulation of phospholipid metabolism by PSS1 and PSS2”. Biochem. J. 342: 57-64. PMID 10432300.
- ↑ Tomohiro, S., Kawaguti, A., Kawabe, Y., Kitada, S. and Kuge, O. (2009). „Purification and characterization of human phosphatidylserine synthases 1 and 2”. Biochem. J. 418: 421-429. PMID 19014349.
Literatura
uredi- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.