Poli(3-hidroksioktanoat) depolimeraza
(Preusmjereno sa stranice PHO depolymerase, poly(3HO) depolymerase)
Poli(3-hidroksioktanoat) depolimeraza (EC 3.1.1.76, PHO depolimeraza, poli(3HO) depolimeraza, poli((R)-hidroksialkanoinska kiselina) depolimeraza, poli(HA) depolimeraza, poli(HAMCL) depolimeraza, poli((R)-3-hidroksioktanoat) hidrolaza) je enzim sa sistematskim imenom poli{oksikarbonil((R)-2-pentiletilen)} hidrolaza.[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Poli(3-hidroksioktanoat) depolimeraza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 3.1.1.76 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- Hidrolizuje poliestar poli{oksikarbonil[(R)-2-pentiletilen]} do oligomera
Glavni produkat nakon duže inkubacije je dimer.
Reference uredi
- ↑ Jendrossek, D. (2001). „Microbial degradation of polyesters”. Adv. Biochem. Eng./Biotechnol. 71: 293-325. PMID 11217416.
- ↑ García, B., Olivera, E.R., Miñambres, B., Fernández-Valverde, Cañedo, L.M., Prieto, M.A., García, J.L., Martínez, M. and Luengo, J.M. (1999). „Novel biodegradable aromatic plastics from a bacterial source. Genetic and biochemical studies on a route of the phenylacetyl-CoA catabolon”. J. Biol. Chem. 274: 29228-29241. PMID 10506180.
- ↑ Schirmer, A., Jendrossek, D. and Schlegel, H.G. (1993). „Degradation of poly(3-hydroxyoctanoic acid) [P(3HO) by bacteria: purification and properties of a P(3HO) depolymerase from Pseudomonas fluorescens GK13”]. Appl. Environ. Microbiol. 59: 1220-1227. PMID 8476295.
Literatura uredi
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.