NADPH:hinon reduktaza
NADPH:hinon reduktaza (EC 1.6.5.5, NADPH2:hinon reduktaza) je enzim sa sistematskim imenom NADPH:hinon oksidoreduktaza.[1][2][3][4] Ovaj enzim katalizuje sledeću hemijsku reakciju
| NADPH:hinon reduktaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 1.6.5.5 | ||||||||
| CAS broj | 9032-20-6 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- NADPH + H+ + 2 hinon NADP+ + 2 semihinon
Ovaj enzim sadrži cink. On je specifičan za NADPH.
Reference uredi
- ↑ Rao, P.V., Krishna, C.M. and Zigler, J.S., Jr. (1992). „Identification and characterization of the enzymatic activity of zeta-crystallin from guinea pig lens. A novel NADPH:quinone oxidoreductase”. J. Biol. Chem. 267: 96-102. PMID 1370456.
- ↑ Duhaiman, A.S. (1996). „Kinetic properties of camel lens ζ-crystallin”. Int. J. Biochem. Cell Biol. 28: 1163-1168. PMID 8930141.
- ↑ Bazzi, M.D. (2001). „Interaction of camel lens ζ-crystallin with quinones: portrait of a substrate by fluorescence spectroscopy”. Arch. Biochem. Biophys. 395: 185-190. PMID 11697855.
- ↑ Tang, A. and Curthoys, N.P. (2001). „Identification of ζ-crystallin/NADPH:quinone reductase as a renal glutaminase mRNA pH response element-binding protein”. J. Biol. Chem. 276: 21375-21380. PMID 11294877.
Literatura uredi
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.