Nikotianamin
(Preusmjereno sa stranice N-(N-(3-amino-3-karboksipropil)-3-amino-3-karboksipropil)azetidin-2-karboksilna kiselina)
Nikotianamin je inhibitor angiotenzin I-konvertujućeg enzima. On je metal-helirajući molekul, koji je sveprisutan kod viših biljki.[4] Biohemijski ovo jedinjenje sintetiše enzim nikotianaminska sintaza, koja koristi tri molekula S-adenozilmetionina.[5]
Nikotianamin | |||
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IUPAC ime |
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Identifikacija | |||
CAS registarski broj | 34441-14-0 | ||
PubChem[1][2] | 7705 | ||
ChemSpider[3] | 8058557 | ||
Jmol-3D slike | Slika 1 | ||
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Svojstva | |||
Molekulska formula | C12H21N3O6 | ||
Molarna masa | 303,31164 g/mol | ||
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Infobox references |
References uredi
- ↑ Li Q, Cheng T, Wang Y, Bryant SH (2010). „PubChem as a public resource for drug discovery.”. Drug Discov Today 15 (23-24): 1052-7. DOI:10.1016/j.drudis.2010.10.003. PMID 20970519.
- ↑ Evan E. Bolton, Yanli Wang, Paul A. Thiessen, Stephen H. Bryant (2008). „Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities”. Annual Reports in Computational Chemistry 4: 217-241. DOI:10.1016/S1574-1400(08)00012-1.
- ↑ Hettne KM, Williams AJ, van Mulligen EM, Kleinjans J, Tkachenko V, Kors JA. (2010). „Automatic vs. manual curation of a multi-source chemical dictionary: the impact on text mining”. J Cheminform 2 (1): 3. DOI:10.1186/1758-2946-2-3. PMID 20331846.
- ↑ Takahashi M, Terada Y, Nakai I, Nakanishi H, Yoshimura E, Mori S, Nishizawa NK. (2003). „Role of nicotianamine in the intracellular delivery of metals and plant reproductive development”. The Plant Cell 15 (6): 1263–80.
- ↑ Zheng L, Cheng Z, Ai C, Jiang X, Bei X, Zheng Y, Glahn RP, Welch RM, Miller DD, Lei XG, Shou H. (2010). „Nicotianamine, a novel enhancer of rice iron bioavailability to humans”. PLOS 5 (4): e10190. DOI:10.1371/journal.pone.0010190.