Koenzim F420 hidrogenaza
Koenzim F420 hidrogenaza (EC 1.12.98.1, 8-hidroksi-5-deazaflavin-redukujuća hidrogenaza, F420-redukujuća hidrogenaza, koenzim F420-zavisna hidrogenaza) je enzim sa sistematskim imenom vodonik:koenzim F420 oksidoreduktaza.[1][2][3][4][5] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Koenzim F420 hidrogenaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 1.12.98.1 | ||||||||
| CAS broj | 2603212 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- H2 + koenzim F420 redukovani koenzim F420
Ovaj gvožđe]-sumporni flavoprotein (FAD) sadrži nikal. Enzim iz pojedinih izvora sadrži selenocistein. Ovaj enzim takođe redukuje riboflavinski analogue F420, flavina i metilviologena, mada u manjoj meri.
Reference
uredi- ↑ Adams, M.W.W., Mortenson, L.E. and Chen, J.-S. (1981). „Hydrogenase”. Biochim. Biophys. Acta 594: 105-176. PMID 6786341.
- ↑ Yamazaki, S. (1982). „A selenium-containing hydrogenase from Methanococcus vannielii. Identification of the selenium moiety as a selenocysteine residue”. J. Biol. Chem. 257: 7926-7929. PMID 6211447.
- ↑ Fox, J.A., Livingston, D.J., Orme-Johnson, W.H. and Walsh, C.T. (1987). „8-Hydroxy-5-deazaflavin-reducing hydrogenase from Methanobacterium thermoautotrophicum: 1. Purification and characterization”. Biochemistry 26: 4219-4228. PMID 3663585.
- ↑ Muth, E., Morschel, E. and Klein, A. (1987). „Purification and characterization of an 8-hydroxy-5-deazaflavin-reducing hydrogenase from the archaebacterium Methanococcus voltae”. Eur. J. Biochem. 169: 571-577. PMID 3121317.
- ↑ Baron, S.F. and Ferry, J.G. (1989). „Purification and properties of the membrane-associated coenzyme F420-reducing hydrogenase from Methanobacterium formicicum”. J. Bacteriol. 171: 3846-3853. PMID 2738024.
Literatura
uredi- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.