Hidrogenaza (akceptor)
Hidrogenaza (akceptor) (EC 1.12.99.6, H2 formirajuća hidrogenaza (nespecifična), vodonična lijaza (nespecifična), hidrogenlijaza (nespecifična), hidrogenaza preuzimanja (nespecifična), vodonik:(akceptor) oksidoreduktaza) je enzim sa sistematskim imenom vodonik:akceptor oksidoreduktaza.[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Hidrogenaza (akceptor) | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 1.12.99.6 | ||||||||
| CAS broj | 2603212 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- H2 + A AH2
Ovaj enzim koristi molekulski vodonik za redukciju raznih supstanci. On sadrži gvožđe-sumporne klustere. Enzim iz pojedinih izvora sadrži nikal.
Reference
uredi- ↑ Shug, A.L., Wilson, P.W., Green, D.E. and Mahler, H.R. (1954). „The role of molybdenum and flavin in hydrogenase”. J. Am. Chem. Soc. 76: 3355-3356.
- ↑ Adams, M.W.W., Mortenson, L.E. and Chen, J.-S. (1981). „Hydrogenase”. Biochim. Biophys. Acta 594: 105-176. PMID 6786341.
- ↑ Vignais, P.M., Billoud, B. and Meyer, J. (2001). „Classification and phylogeny of hydrogenases”. FEMS Microbiol. Rev. 25: 455-501. PMID 11524134.
Literatura
uredi- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.