Feredoksin hidrogenaza
(Preusmjereno sa stranice H2 oxidizing hydrogenase)
Feredoksin hidrogenaza (EC 1.12.7.2, H2 oksidaciona hidrogenaza, H2 formirajuća hidrogenaza (nespecifična), bidirekciona hidrogenaza, vodonična lijaza (nespecifična), hidrogenaza (feredoksin), hidrogenaza I, hidrogenaza II) je enzim sa sistematskim imenom vodonik:feredoksin oksidoreduktaza.[1][2][3][4][5][6] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Feredoksin hidrogenaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 1.12.7.2 | ||||||||
| CAS broj | 2603212 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- H2 + 2 oksidovani feredoksin 2 redukovani feredoksin + 2 H+
Ovaj enzim sadrži gvožđe-sumporne klustere. Enzimi iz nekih izvora sadrže nikal.
Reference uredi
- ↑ Shug, A.L., Wilson, P.W., Green, D.E. and Mahler, H.R. (1954). „The role of molybdenum and flavin in hydrogenase”. J. Am. Chem. Soc. 76: 3355-3356.
- ↑ Tagawa, K. and Arnon, D.I. (1962). „Ferredoxin as electron carriers in photosynthesis and in the bioogical production and consumption of hydrogen gas”. Nature (Lond.) 195: 537-543.
- ↑ Valentine, R.C., Mortenson, L.E. and Carnahan, J.E. (1963). „The hydrogenase system of Clostridium pasteurianum”. J. Biol. Chem. 238: 1141-1144.
- ↑ Zumft, W.G. and Mortenson, L.E. (1975). „The nitrogen-fixing complex of bacteria”. Biochim. Biophys. Acta 416: 1-52. PMID 164247.
- ↑ Adams, M.W.W. (1990). „The structure and mechanism of iron-hydrogenases”. Biochim. Biophys. Acta 1020: 115-145. PMID 2173950.
- ↑ Peters, J.W., Lanzilotta, W.N., Lemon, B.J. and Seefeldt, L.C. (1998). „X-ray crystal structure of the Fe-only hydrogenase (Cpl) from Clostridium pasteurianum to 1.8 Angstrom resolution”. Science 282: 1853-1858. PMID 9836629.
Literatura uredi
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.