Gadodiamid je na gadolinijumu baziran kontrastni agens koji se koristi u procedurama za MR snimanje. On pomaže u vizualizaciji krvnih sudova. Ovaj leki je u prodaji pod imenom Omniscan.[5][6]
Gadodiamid
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| (IUPAC) ime
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| gadolinijum(3+) jon 2-[bis({2-[(karboksilatometil)[(metilkarbamoil)metil]amino]etil})amino]acetat hidrat
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| Klinički podaci
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| AHFS/Drugs.com
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Monografija
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| Identifikatori
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| CAS broj
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122795-43-1
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| ATC kod
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V08CA03
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| PubChem[1][2]
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60754
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| DrugBank
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DB00225
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| ChemSpider[3]
|
54756
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| KEGG[4]
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C13106  Y
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| Hemijski podaci
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| Formula
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C16H28N5O9
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| Mol. masa
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591.67
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| SMILES
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eMolekuli & PubHem
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| InChI |
|---|
InChI=1S/C16H29N5O8.Gd.H2O/c1-17-12(22)7-20(10-15(26)27)5-3-19(9-14(24)25)4-6-21(11-16(28)29)8-13(23)18-2;;/h3-11H2,1-2H3,(H,17,22)(H,18,23)(H,24,25)(H,26,27)(H,28,29);;1H2/q;+3;/p-3
Key: XPCLDSMKWNNKOM-UHFFFAOYSA-K Y |
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| Farmakokinetički podaci
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| Poluvreme eliminacije
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3,7 sati
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| Izlučivanje
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Uglavnom urinom
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| Farmakoinformacioni podaci
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| Trudnoća
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?
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| Pravni status
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| Način primene
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Intravenozno
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- ↑ Li Q, Cheng T, Wang Y, Bryant SH (2010). „PubChem as a public resource for drug discovery.”. Drug Discov Today 15 (23-24): 1052-7. DOI:10.1016/j.drudis.2010.10.003. PMID 20970519. edit
- ↑ Evan E. Bolton, Yanli Wang, Paul A. Thiessen, Stephen H. Bryant (2008). „Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities”. Annual Reports in Computational Chemistry 4: 217-241. DOI:10.1016/S1574-1400(08)00012-1.
- ↑ Hettne KM, Williams AJ, van Mulligen EM, Kleinjans J, Tkachenko V, Kors JA. (2010). „Automatic vs. manual curation of a multi-source chemical dictionary: the impact on text mining”. J Cheminform 2 (1): 3. DOI:10.1186/1758-2946-2-3. PMID 20331846. edit
- ↑ Joanne Wixon, Douglas Kell (2000). „Website Review: The Kyoto Encyclopedia of Genes and Genomes — KEGG”. Yeast 17 (1): 48–55. DOI:10.1002/(SICI)1097-0061(200004)17:1<48::AID-YEA2>3.0.CO;2-H.
- ↑ Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS (2011). „DrugBank 3.0: a comprehensive resource for omics research on drugs”. Nucleic Acids Res. 39 (Database issue): D1035-41. PMID 21059682.
- ↑ Wishart DS, Knox C, Guo AC, Cheng D, Shrivastava S, Tzur D, Gautam B, Hassanali M (2008). „DrugBank: a knowledgebase for drugs, drug actions and drug targets”. Nucleic Acids Res 36 (Database issue): D901-6. PMID 18048412.
