Lizinska karboksipeptidaza
(Preusmjereno sa stranice CPase N)
Lizinska karboksipeptidaza (EC 3.4.17.3, karboksipeptidaza N, argininska karboksipeptidaza, kininaza I, anafilatoksinski inaktivator, karboksipeptidaza B plazme, faktor konverzije kreatinske kinaze, bradikinaza, kininaza Ia, hipurilizinska hidrolaza, enzim razlaganja bradikinina, protaminaza, CPaze N, kreatinin kinazna konvertaza, peptidilna-L-lizin(-L-arginin) hidrolaza, CPN) je enzim.[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Lizinska karboksipeptidaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 3.4.17.3 | ||||||||
| CAS broj | 9013-89-2 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- Odvajanje C-terminalne bazne aminokiseline, preferentno lizina.
Ovaj cinkov enzim je prisutan u plazmi.
Reference uredi
- ↑ Plummer, T.H., Jr. and Erdös, E.G. (1981). „Human plasma carboxypeptidase N”. Methods Enzymol. 80: 442-449. PMID 7341915.
- ↑ Levin, Y., Skidgel, R.A. and Erdös, E.G. (1982). „Isolation and characterization of the subunits of human plasma carboxypeptidase N (kininase I)”. Proc. Natl. Acad. Sci. USA 79: 4618-4622. PMID 6750606.
- ↑ Skidgel, R.A. (1988). „Basic carboxypeptidases: regulators of peptide hormone activity”. Trends Pharmacol. Sci. 9: 301-303. PMID 3074547.
Literatura uredi
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.