Beta-karoten 15,15'-dioksigenaza
Beta-karoten 15,15'-dioksigenaza (EC 1.13.11.63, blh (gen)) je enzim sa sistematskim imenom beta-karoten:kiseonik 15,15'-dioksigenaza (razlaganje veze).[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Beta-karoten 15,15'-dioksigenaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 1.13.11.63 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- beta-karoten + O2 2 sve-trans-retinal
Ovaj enzim sadrži Fe2+. Enzim iz morskih bakterija 66A03 učestvuje u proteorodopsinskom sistemu koji koristi retinal kao hromofor.
Reference uredi
- ↑ Kim, Y.S., Kim, N.H., Yeom, S.J., Kim, S.W. and Oh, D.K. (2009). „In vitro characterization of a recombinant Blh protein from an uncultured marine bacterium as a β-carotene 15,15′-dioxygenase”. J. Biol. Chem. 284: 15781-15793. PMID 19366683.
- ↑ Kim, Y.S., Park, C.S. and Oh, D.K. (2010). „Retinal production from β-carotene by β-carotene 15,15′-dioxygenase from an unculturable marine bacterium”. Biotechnol. Lett. 32: 957-961. PMID 20229064.
Literatura uredi
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.