Arildialkilfosfataza
Arildialkilfosfataza (EC 3.1.8.1, organofosfatna hidrolaza, paraoksonaza, A-esteraza, ariltrifosfataza, organofosfatna esteraza, esteraza B1, esteraza E4, paraoksonska esteraza, pirimifos-metilokson esteraza, OPA anhidraza, organofosforna hidrolaza, fosfotriesteraza, paraoksonska hidrolaza, OPH, organofosforno kiselinska anhidraza) je enzim sa sistematskim imenom ariltrifosfat dialkilfosfohidrolaza.[1][2][3][4][5] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Arildialkilfosfataza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 3.1.8.1 | ||||||||
| CAS broj | 117698-12-1 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
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Ovaj enzim deluje na organofosforna jedinjenja (poput paraoksona) uključujući estre fosfone i hipofosforaste kiseline.
Reference
uredi- ↑ Aldridge, W.N. (1953). „Serum esterases. I. Two types of esterase (A and B) hydrolysing p-nitrophenyl acetate, propionate and butyrate and a method for their determination”. Biochem. J. 53: 110-117. PMID 13032041.
- ↑ Bosmann, H.B. (1972). „Membrane marker enzymes. Characterization of an arylesterase of guinea pig cerebral cortex utilizing p-nitrophenyl acetate as substrate”. Biochim. Biophys. Acta 276: 180-191. PMID 5047702.
- ↑ Mackness, M.I., Thompson, H.M., Hardy, A.R. and Walker, C.H. (1987). „Distinction between 'A′-esterases and arylesterases. Implications for esterase classification”. Biochem. J. 245: 293-296. PMID 2822017.
- ↑ Main, A.R. (1960). „The differentiation of the A-type esterases in sheep serum”. Biochem. J. 75: 188-195. PMID 14420012.
- ↑ Reiner, E., Aldridge, W.N. and Hoskin, C.G., ur. (1989). Enzymes Hydrolysing Organophosphorus Compounds. Chichester, UK: Ellis Horwood. str. -.
Literatura
uredi- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.
- Reiner, E., Aldridge, W.N. and Hoskin, C.G., ur. (1989). Enzymes Hydrolysing Organophosphorus Compounds. Chichester, UK: Ellis Horwood. str. -.