Acetoacetatna dekarboksilaza
Acetoacetatna dekarboksilaza (EC 4.1.1.4, acetoacetinsko kiselinska dekarboksilaza, acetoacetatna karboksi-lijaza) je enzim sa sistematskim imenom acetoacetat karboksi-lijaza (formira aceton).[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Acetoacetatna dekarboksilaza | |||||||||
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| Identifikatori | |||||||||
| EC broj | 4.1.1.4 | ||||||||
| CAS broj | 9025-03-0 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
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- acetoacetat + H+ aceton + CO2
Reference uredi
- ↑ Davies, R. (1943). „Studies of the acetone-butanol fermentation. 4. Acetoacetic acid decarboxylase of Cl. acetobutylicum (BY)”. Biochem. J. 37: 230-238. PMID 16747621.
- ↑ Zerner, B., Coutts, S.M., Lederer, F., Waters, H.H. and Westheimer, F.H. (1966). „Acetoacetate decarboxylase. Preparation of the enzyme”. Biochemistry 5: 813-816. PMID 5911291.
- ↑ Ho, M.C., Menetret, J.F., Tsuruta, H. and Allen, K.N. (2009). „The origin of the electrostatic perturbation in acetoacetate decarboxylase”. Nature 459: 393-397. PMID 19458715.
Literatura uredi
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.