Acetilenska hidrataza
Acetilenska hidrataza (EC 4.2.1.112, AH, acetaldehidna hidrolijaza) je enzim sa sistematskim imenom acetaldehid hidrolijaza (formira acetilen).[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Acetilenska hidrataza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 4.2.1.112 | ||||||||
| CAS broj | 75788-81-7 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- acetaldehid acetilen + H2O
Ovaj neredoks-aktivni enzim sadrži dva molibdopterin guanin dinukleotid (MGD) kofaktora.
Reference uredi
- ↑ Rosner, B.M. and Schink, B. (1995). „Purification and characterization of acetylene hydratase of Pelobacter acetylenicus, a tungsten iron-sulfur protein”. J. Bacteriol. 177: 5767-5772. PMID 7592321.
- ↑ Seiffert, G.B., Ullmann, G.M., Messerschmidt, A., Schink, B., Kroneck, P.M. and Einsle, O. (2007). „Structure of the non-redox-active tungsten/[4Fe:4S] enzyme acetylene hydratase”. Proc. Natl. Acad. Sci. USA 104: 3073-3077. PMID 17360611.
Literatura uredi
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.