7-Dimetilaliltriptofan sintaza
(Preusmjereno sa stranice 7-dimetilaliltriptofan sintaza)
7-dimetilaliltriptofan sintaza (EC 2.5.1.80, 7-DMATS) je enzim sa sistematskim imenom dimetilalil-difosfat:L-triptofan 7-dimetilalilna transferaza.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
| 7-dimetilaliltriptofan sintaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 2.5.1.80 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- dimetilalil difosfat + L-triptofan difosfat + 7-(3-metilbut-2-enil)-L-triptofan
Ovaj enzim je efektivniji na aromatičnim supstratima od EC 2.5.1.34 (4-dimetilaliltriptofanske sintaze).
Reference uredi
- ↑ Kremer, A. and Li, S.M. (2008). „Potential of a 7-dimethylallyltryptophan synthase as a tool for production of prenylated indole derivatives”. Appl. Microbiol. Biotechnol. 79: 951-961. PMID 18481055.
- ↑ Kremer, A., Westrich, L. and Li, S.M. (2007). „A 7-dimethylallyltryptophan synthase from Aspergillus fumigatus: overproduction, purification and biochemical characterization”. Microbiology 153: 3409-3416. PMID 17906140.
Literatura uredi
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.