1,2-dihidroksinaftalen dioksigenaza
1,2-dihidroksinaftalen dioksigenaza (EC 1.13.11.56, 1,2-DHN dioksigenaza, DHNDO, 1,2-dihidroksinaftalenska oksigenaza, 1,2-dihidroksinaftalen:kiseonik oksidoreduktaza) je enzim sa sistematskim imenom naftalen-1,2-diol:kiseonik oksidoreduktaza.[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
| 1,2-dihidroksinaftalen dioksigenaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
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| 1,2-dihidroksinaftalen dioksigenaza oktamer, Pseudomonas | |||||||||
| Identifikatori | |||||||||
| EC broj | 1.13.11.56 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- naftalen-1,2-diol + O2 2-hidroksi-2H-hromen-2-karboksilat
Ovaj enzim učestvuje u degradaciji naftalena. Za njegov rad je neophodan jon Fe2+.
Reference
uredi- ↑ Kuhm, A.E., Stolz, A., Ngai, K.L. and Knackmuss, H.J. (1991). „Purification and characterization of a 1,2-dihydroxynaphthalene dioxygenase from a bacterium that degrades naphthalenesulfonic acids”. J. Bacteriol. 173: 3795-3802. PMID 2050635.
- ↑ Keck, A., Conradt, D., Mahler, A., Stolz, A., Mattes, R. and Klein, J. (2006). „Identification and functional analysis of the genes for naphthalenesulfonate catabolism by Sphingomonas xenophaga BN6”. Microbiology 152: 1929-1940. PMID 16804169.
- ↑ Patel, T.R. and Barnsley, E.A. (1980). „Naphthalene metabolism by pseudomonads: purification and properties of 1,2-dihydroxynaphthalene oxygenase”. J. Bacteriol. 143: 668-673. PMID 7204331.
Literatura
uredi- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.