X-Pro aminopeptidaza
(Preusmjereno sa stranice X-Pro-aminopeptidaza)
X-Pro aminopeptidaza (EC 3.4.11.9, prolinska aminopeptidaza, aminopeptidaza P, aminoacilprolinska aminopeptidaza) je enzim.[1][2][3][4][5] Ovaj enzim katalizuje sledeću hemijsku reakciju
| X-Pro aminopeptidaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 3.4.11.9 | ||||||||
| CAS broj | 37288-66-7 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- Odvajanje N-terminalne aminokiseline, uključujući prolin, koja je vezana za prolin, čak i iz dipeptida ili tripeptida
Ovaj enzim je zavistan od jona Mn2+.
Reference uredi
- ↑ Yaron, A. and Mlynar, D. (1968). „Aminopeptidase-P”. Biochem. Biophys. Res. Commun. 32: 658-663. PMID 4878817.
- ↑ Yaron, A. and Berger, A. (1970). „Aminopeptidase-P”. Methods Enzymol. 19: 522-534.
- ↑ Fleminger, G., Carmel, A. and Yaron, A. (1982). „Fluorogenic substrates for bacterial aminopeptidase P and its analogs detected in human serum and calf lung”. Eur. J. Biochem. 125: 609-615. PMID 6749499.
- ↑ Orawski, A.T., Susz, J.P. and Simmons, W.H. (1987). „Aminopeptidase-P from bovine lung - solubilization, properties, potential role in bradykinin degradation”. Mol. Cell. Biochem. 75: 123-132. PMID 3627107.
- ↑ Hooper, N.M., Hryszko, J. and Turner, A.J. (1990). „Purification and characterization of pig kidney aminopeptidase P”. Biochem. J. 267: 509-515. PMID 2139778.
Literatura uredi
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.