VN1R1
(Preusmjereno sa stranice V1RL1)
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Vomeronazalni tip-1 receptor 1 je protein koji je kod ljudi kodiran VN1R1 genom.[1][2]
| Vomeronazalni tip-1 receptor 1 | |||||||||||
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| Identifikatori | |||||||||||
| Simboli | VN1R1; V1RL1; VNR19I1; ZVNH1; ZVNR1 | ||||||||||
| Vanjski ID | OMIM: 605234 HomoloGene: 110801 GeneCards: VN1R1 Gene | ||||||||||
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| Pregled RNK izražavanja | |||||||||||
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| Ortolozi | |||||||||||
| Vrsta | Čovek | Miš | |||||||||
| Entrez | 57191 | n/a | |||||||||
| Ensembl | ENSG00000178201 | n/a | |||||||||
| UniProt | Q9GZP7 | n/a | |||||||||
| RefSeq (mRNA) | NM_020633.3 | n/a | |||||||||
| RefSeq (protein) | NP_065684.1 | n/a | |||||||||
| Lokacija (UCSC) | Chr 19: 57.97 - 57.97 Mb | n/a | |||||||||
| PubMed pretraga | [1] | n/a | |||||||||
Feromoni su hemijski signali koji izazivaju specifične oblike ponašanja i fiziološke alteracije kod recipijenata iste vrste. Protein kodiran ovim genom je sličan sa feromonskim receptorima i prvenstveno je lokalizovan u mirisnoj sluzokoži. Alternativne splajsne varijante ovog gena su poznate. Njegova funkcija nije dovoljno izučena.[2]
Reference
uredi- ↑ Rodriguez I, Greer CA, Mok MY, Mombaerts P (Oct 2000). „A putative pheromone receptor gene expressed in human olfactory mucosa”. Nat Genet 26 (1): 18–9. DOI:10.1038/79124. PMID 10973240.
- ↑ 2,0 2,1 „Entrez Gene: VN1R1 vomeronasal 1 receptor 1”.
Literatura
uredi- Giorgi D, Friedman C, Trask BJ, Rouquier S (2001). „Characterization of nonfunctional V1R-like pheromone receptor sequences in human”. Genome Res. 10 (12): 1979–85. DOI:10.1101/gr.10.12.1979. PMC 313059. PMID 11116092.
- Pantages E, Dulac C (2001). „A novel family of candidate pheromone receptors in mammals”. Neuron 28 (3): 835–45. DOI:10.1016/S0896-6273(00)00157-4. PMID 11163270.
- Takeda S, Kadowaki S, Haga T, et al. (2002). „Identification of G protein-coupled receptor genes from the human genome sequence”. FEBS Lett. 520 (1–3): 97–101. DOI:10.1016/S0014-5793(02)02775-8. PMID 12044878.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2003). „Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences”. Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. DOI:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
- Zhang J, Webb DM (2003). „Evolutionary deterioration of the vomeronasal pheromone transduction pathway in catarrhine primates”. Proc. Natl. Acad. Sci. U.S.A. 100 (14): 8337–41. DOI:10.1073/pnas.1331721100. PMC 166230. PMID 12826614.
- Ota T, Suzuki Y, Nishikawa T, et al. (2004). „Complete sequencing and characterization of 21,243 full-length human cDNAs”. Nat. Genet. 36 (1): 40–5. DOI:10.1038/ng1285. PMID 14702039.
- Gerhard DS, Wagner L, Feingold EA, et al. (2004). „The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)”. Genome Res. 14 (10B): 2121–7. DOI:10.1101/gr.2596504. PMC 528928. PMID 15489334.
- Mitropoulos C, Papachatzopoulou A, Menounos PG, et al. (2007). „Association study of human VN1R1 pheromone receptor gene alleles and gender”. Genet. Test. 11 (2): 128–32. DOI:10.1089/gte.2006.0516. PMID 17627382.