Uridin kinaza
Uridin kinaza (EC 2.7.1.48, pirimidin ribonukleozidna kinaza, uridin-citidin kinaza, uridin kinaza (fosforilacija), uridinska fosfokinaza) je enzim sa sistematskim imenom ATP:uridin 5'-fosfotransferaza.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Uridin kinaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| |||||||||
| Tetramer uridin kinaze 2 (čovjek) | |||||||||
| Identifikatori | |||||||||
| EC broj | 2.7.1.48 | ||||||||
| CAS broj | 9026-39-5 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
Citidin može da deluje kao akceptor. GTP i ITP mogu da deluju kao donori.
Reference uredi
- ↑ Orengo, A. (1969). „Regulation of enzymic activity by metabolites. I. Uridine-cytidine kinase of Novikoff ascites rat tumor”. J. Biol. Chem. 244: 2204-2209. PMID 5782006.
- ↑ Sköld, O. (1960). „Uridine kinase from Erlich ascites tumor: purification and properties”. J. Biol. Chem. 235: 3273-3279.
Literatura uredi
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.