Undekaprenildifosfo-muramoilpentapeptid b-N-acetilglukozaminiltransferaza
(Preusmjereno sa stranice Undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase)
Undekaprenildifosfo-muramoilpentapeptid b-N-acetilglukozaminiltransferaza (EC 2.4.1.227, MurG transferaza, UDP-N-acetil-D-glukozamin:N-acetil-alfa-D-muramil(oil-L-Ala-gama-D-Glu-L-Lys-D-Ala-D-Ala)-difosfoundekaprenol beta-1,4-N-acetilglukozaminltransferaza) je enzim sa sistematskim imenom UDP-N-acetil-D-glukozamin:N-acetil-alfa-D-muramil(oil-L-Ala-gama-D-Glu-L-Lis-D-Ala-D-Ala)-difosfoundekaprenol 4-beta-N-acetilglukosaminlitransferaza.[1] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Undekaprenildifosfo-muramoilpentapeptid b-N-acetilglukozaminiltransferaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 2.4.1.227 | ||||||||
| CAS broj | 60976-26-3 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- UDP-N-acetilglukozamin + Mur2Ac(oil-L-Ala-gama-D-Glu-L-Lys-D-Ala-D-Ala)-difosfoundekaprenol UDP + GlcNAc-(1->4)-Mur2Ac(oil-L-Ala-gama-D-Glu-L-Lys-D-Ala-D-Ala)-difosfoundekaprenol
Ovaj enzim takođe deluje kad se lizinski ostatak zameni meso-2,6-diaminoheptanedioatom (meso-2,6-diaminopimelat, A2pm) u kombinaciji sa ostacima.
Reference uredi
Literatura uredi
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.