5'-Nukleotidaza
(Preusmjereno sa stranice UMPaze)
5'-nukleotidaza (EC 3.1.3.5, uridinska 5'-nukleotidaza, 5'-adenilna fosfataza, adenozinska 5'-fosfataza, AMP fosfataza, adenozinska monofosfataza, 5'-mononukleotidaza, AMPaze, UMPaze, 5'-nukleotidaza zmijskog venuma, timidinska monofosfatna nukleotidaza, 5'-AMPaza, 5'-AMP nukleotidaza, AMP fosfohidrolaza, IMP 5'-nukleotidaza) je enzim sa sistematskim imenom 5'-ribonukleotid fosfohidrolaza.[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
| 5'-nukleotidaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| |||||||||
| 5'-nukleotidaza dimer, Human | |||||||||
| Identifikatori | |||||||||
| EC broj | 3.1.3.5 | ||||||||
| CAS broj | 9027-73-0 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- 5'-ribonukleotid + H2O ribonukleozid + fosfat
Ovaj enzim ima široku specifičnost za 5'-nukleotide.
Reference
uredi- ↑ Gulland, J.M. and Jackson, E.M. (1938). „5-Nucleotidase”. Biochem. J. 32: 597-601. PMID 16746659.
- ↑ Heppel, L.A. and Hilmoe, R.J. (1951). „Purification and properties of 5-nucleotidase”. J. Biol. Chem. 188: 665-676. PMID 14824154.
- ↑ Segal, H.L. and Brenner, B.M. (1960). „5′-Nucleotidase of rat liver microsomes”. J. Biol. Chem. 235: 471-474. PMID 14444527.
Literatura
uredi- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.