Tritrans,policis-undekaprenil-difosfat sintaza (geranilgeranil-difosfat specifična)
Tritrans,policis-undekaprenil-difosfat sintaza (geranilgeranil-difosfat specifična) (EC 2.5.1.89, Tritrans,polycis-undecaprenyl-diphosphate synthase (geranylgeranyl-diphosphate specific)) je enzim sa sistematskim imenom geranilgeranil-difosfat:izopentenil-difosfat cistransferaza (dodaje 7 izopentenilnih jedinica).[1] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Tritrans,policis-undekaprenil-difosfat sintaza (geranilgeranil-difosfat specifična) | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 2.5.1.89 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- geranilgeranil difosfat + 7 izopentenil difosfat 7 difosfat + tritrans,heptacis-undekaprenil difosfat
Ovaj enzim učestvuje u biosintezi glikozilnog nosiola lipida kod pojedinih arhebakterija.
Reference uredi
- ↑ Hemmi, H., Yamashita, S., Shimoyama, T., Nakayama, T. and Nishino, T. (2001). „Cloning, expression, and characterization of cis-polyprenyl diphosphate synthase from the thermoacidophilic archaeon Sulfolobus acidocaldarius”. J. Bacteriol. 183: 401-404. PMID 11114943.
Literatura uredi
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.