Trans-2-enoil-KoA reduktaza (NADPH)
Trans-2-enoil-KoA reduktaza (NADPH) (EC 1.3.1.38, NADPH-zavisni trans-2-enoil-KoA reduktaza, reduktaza, trans-enoil koenzim A, trans-2-enoil-KoA reduktaza (NADPH2)) je enzim sa sistematskim imenom acil-KoA:NADP+ trans-2-oksidoreduktaza.[1] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Trans-2-enoil-KoA reduktaza (NADPH) | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 1.3.1.38 | ||||||||
| CAS broj | 77649-64-0 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- acil-KoA + NADP+ trans-2,3-dehidroacil-KoA + NADPH + H+
Ovaj enzim nije identičan sa EC 1.3.1.37, cis-2-enoil-KoA reduktazom (NADPH), cf. EC 1.3.1.8, acil-KoA dehidrogenaza (NADP}+).
Reference uredi
- ↑ Mizugaki, M., Nishimaki, T., Shiraishi, T., Kawaguchi, A., Okuda, S. and Yamanaka, H. (1982). „Studies on the metabolism of unsaturated fatty acids. IX. Stereochemical studies of the reaction catalyzed by trans-2-enoyl-coenzyme A reductase of Escherichia coli”. J. Biochem. (Tokyo) 92: 1649-1654. PMID 6759504.
Literatura uredi
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.