Taurin—piruvat aminotransferaza
Taurin—piruvat aminotransferaza (EC 2.6.1.77, Tpa) je enzim sa sistematskim imenom taurin:piruvat aminotransferaza.[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Taurin—piruvat aminotransferaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 2.6.1.77 | ||||||||
| CAS broj | 51901-18-9 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
Za rad enzima iz Bilophila wadsworthia je neophodan piridoksal 5'-fosfat kao kofaktor.
Reference
uredi- ↑ Laue, H. and Cook, A.M. (2000). „Biochemical and molecular characterization of taurine:pyruvate transaminase from the anaerobe Bilophila wadsworthia”. Eur. J. Biochem. 267: 6841-6848. PMID 11082195.
- ↑ Cook, A.M. and Denger, K. (2002). „Dissimilation of the C2 sulfonates”. Arch. Microbiol. 179: 1-6. PMID 12471498.
- ↑ Masepohl, B., Fuhrer, F. and Klipp, W. (2001). „Genetic analysis of a Rhodobacter capsulatus gene region involved in utilization of taurine as a sulfur source”. FEMS Microbiol. Lett. 205: 105-111. PMID 11728723.
Literatura
uredi- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.