TRNK (guanin-N1-)-metiltransferaza (EC 2.1.1.31, transfer ribonukleat guaninska 1-metiltransferaza, tRNK guaninska 1-metiltransferaza, S-adenozil-L-metionin:tRNK (guanin-1-N-)-metiltransferaza) je enzim sa sistematskim imenom S-adenozil-L-metionin:tRNK (guanin-N1-)-metiltransferaza.[1][2][3][4] Ovaj enzim katalizuje sledeću hemijsku reakciju
- S-adenozil-L-metionin + tRNK S-adenozil-L-homocistein + tRNK sa N1-metilguaninom
- ↑ Björk, G.R. and Svensson, I. (1969). „Studies on microbial RNA. Fractionation of tRNA methylases from Saccharomyces cerevisiae”. Eur. J. Biochem. 9: 207-215. PMID 4896260.
- ↑ Glick, J.M., Averyhart, V.M. and Leboy, P.S. (1978). „Purification and characterization of two tRNA-(guanine)-methyltransferases from rat liver”. Biochim. Biophys. Acta 518: 158-171. PMID 629973.
- ↑ Hurwitz, J., Gold, M. and Anders, M. (1964). „The enzymatic methylation of ribonucleic acid and deoxyribonucleic acid. 3. Purification of soluble ribonucleic acid-methylating enzymes”. J. Biol. Chem. 239: 3462-3473. PMID 14245404.
- ↑ Smolar, N., Hellman, V. and Svennson, I. (1975). „Two transfer RNA (1-methylguanine) methylases from yeast”. Nucleic Acids Res. 2: 993-1004. PMID 1096087.
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