TPTE
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TPTE (engl. Putative tyrosine-protein phosphatase) je enzim koji je kod ljudi kodiran TPTE genom.[1][2][3]
| Transmembranska fosfataza sa tenzinskom homologijom | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||||
| Simboli | TPTE; CT44; PTEN2 | ||||||||||
| Vanjski ID | OMIM: 604336 MGI: 2446460 HomoloGene: 50411 GeneCards: TPTE Gene | ||||||||||
| EC broj | 3.1.3.48 | ||||||||||
| |||||||||||
| Ortolozi | |||||||||||
| Vrsta | Čovek | Miš | |||||||||
| Entrez | 7179 | 234129 | |||||||||
| Ensembl | ENSG00000166157 | ENSMUSG00000031481 | |||||||||
| UniProt | P56180 | E9Q3G1 | |||||||||
| RefSeq (mRNA) | NM_199259.2 | NM_181851.3 | |||||||||
| RefSeq (protein) | NP_954868.1 | NP_954866.2 | |||||||||
| Lokacija (UCSC) | Chr 21: 10.91 - 11.03 Mb | Chr 8: 23.39 - 23.48 Mb | |||||||||
| PubMed pretraga | [1] | [2] | |||||||||
TPIP je član velike klase za membranu vezanih fosfataza sa supstratnom specifičnošću za fosfat u 3-poziciji inozitolnih fosfolipida.[3]
Reference uredi
- ↑ Hattori M, Fujiyama A, Taylor TD, Watanabe H, Yada T, Park HS, Toyoda A, Ishii K, Totoki Y, Choi DK, Groner Y, Soeda E, Ohki M, Takagi T, Sakaki Y, Taudien S, Blechschmidt K, Polley A, Menzel U, Delabar J, Kumpf K, Lehmann R, Patterson D, Reichwald K, Rump A, Schillhabel M, Schudy A, Zimmermann W, Rosenthal A, Kudoh J, Schibuya K, Kawasaki K, Asakawa S, Shintani A, Sasaki T, Nagamine K, Mitsuyama S, Antonarakis SE, Minoshima S, Shimizu N, Nordsiek G, Hornischer K, Brant P, Scharfe M, Schon O, Desario A, Reichelt J, Kauer G, Blocker H, Ramser J, Beck A, Klages S, Hennig S, Riesselmann L, Dagand E, Haaf T, Wehrmeyer S, Borzym K, Gardiner K, Nizetic D, Francis F, Lehrach H, Reinhardt R, Yaspo ML (Jun 2000). „The DNA sequence of human chromosome 21”. Nature 405 (6784): 311–9. DOI:10.1038/35012518. PMID 10830953.
- ↑ Tapparel C, Reymond A, Girardet C, Guillou L, Lyle R, Lamon C, Hutter P, Antonarakis SE (Dec 2003). „The TPTE gene family: cellular expression, subcellular localization and alternative splicing”. Gene 323: 189–99. DOI:10.1016/j.gene.2003.09.038. PMID 14659893.
- ↑ 3,0 3,1 „Entrez Gene: TPTE transmembrane phosphatase with tensin homology”.
Literatura uredi
- Antonarakis SE (1998). „10 years of Genomics, chromosome 21, and Down syndrome.”. Genomics 51 (1): 1–16. DOI:10.1006/geno.1998.5335. PMID 9693027.
- Chen H, Rossier C, Morris MA, et al. (2000). „A testis-specific gene, TPTE, encodes a putative transmembrane tyrosine phosphatase and maps to the pericentromeric region of human chromosomes 21 and 13, and to chromosomes 15, 22, and Y.”. Hum. Genet. 105 (5): 399–409. DOI:10.1007/s004390051122. PMID 10598804.
- Guipponi M, Yaspo ML, Riesselman L, et al. (2000). „Genomic structure of a copy of the human TPTE gene which encompasses 87 kb on the short arm of chromosome 21.”. Hum. Genet. 107 (2): 127–31. DOI:10.1007/s004390000343. PMID 11030409.
- Wu Y, Dowbenko D, Pisabarro MT, et al. (2001). „PTEN 2, a Golgi-associated testis-specific homologue of the PTEN tumor suppressor lipid phosphatase.”. J. Biol. Chem. 276 (24): 21745–53. DOI:10.1074/jbc.M101480200. PMID 11279206.
- Guipponi M, Tapparel C, Jousson O, et al. (2002). „The murine orthologue of the Golgi-localized TPTE protein provides clues to the evolutionary history of the human TPTE gene family.”. Hum. Genet. 109 (6): 569–75. DOI:10.1007/s004390100607. PMID 11810268.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2003). „Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.”. Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. DOI:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
- Gerhard DS, Wagner L, Feingold EA, et al. (2004). „The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).”. Genome Res. 14 (10B): 2121–7. DOI:10.1101/gr.2596504. PMC 528928. PMID 15489334.