TDP-4-okso-6-dezoksi-alfa-D-glukoza-3,4-oksoizomeraza (formira dTDP-3-dehidro-6-dezoksi-alfa-D-galaktopiranoza)
TDP-4-okso-6-dezoksi-alfa-D-glukoza-3,4-oksoizomeraza (formira dTDP-3-dehidro-6-dezoksi-alfa-D-galaktopiranoza) (EC 5.3.2.3, dTDP-6-dezoksi-heks-4-uloza izomeraza, TDP-6-dezoksi-heks-4-uloza izomeraza, FdtA) je enzim sa sistematskim imenom dTDP-4-dehidro-6-dezoksi-alfa-D-glukopiranoza:dTDP-3-dehidro-6-dezoksi-alfa-D-galaktopiranoza izomeraza.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
| TDP-4-okso-6-dezoksi-alfa-D-glukoza-3,4-oksoizomeraza (formira dTDP-3-dehidro-6-dezoksi-alfa-D-galaktopiranoza) | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 5.3.2.3 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
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- dTDP-4-dehidro-6-dezoksi-alfa-D-glukopiranoza dTDP-3-dehidro-6-dezoksi-alfa-D-galaktopiranoza
Ovaj enzim učestvuje u biosintezi dTDP-3-acetamido-3,6-didezoksi-alfa-D-galaktoze.
Reference
uredi- ↑ Pfoestl, A., Hofinger, A., Kosma, P. and Messner, P. (2003). „Biosynthesis of dTDP-3-acetamido-3,6-dideoxy-α-D-galactose in Aneurinibacillus thermoaerophilus L420-91T”. J. Biol. Chem. 278: 26410-26417. PMID 12740380.
- ↑ Davis, M.L., Thoden, J.B. and Holden, H.M. (2007). „The x-ray structure of dTDP-4-keto-6-deoxy-D-glucose-3,4-ketoisomerase”. J. Biol. Chem. 282: 19227-19236. PMID 17459872.
Literatura
uredi- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.