Dezoksiribonukleaza (pirimidinskog dimera)
(Preusmjereno sa stranice T4 endonuclease V)
Dezoksiribonukleaza (pirimidinskog dimera) (EC 3.1.25.1, endodezoksiribonukleaza (pirimidinski dimer), bakteriofag T4 endodezoksiribonukleaza V, T4 endonukleaza V) je enzim.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Dezoksiribonukleaza (pirimidinskog dimera) | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 3.1.25.1 | ||||||||
| CAS broj | 66143-22-4 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
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- Endonukleolitičko razlaganje blizo pirimidinskih dimera do produkata sa 5'-fosfatom
Ovi enzim deluju na oštećene DNK lance, 5' sa mesta oštećenja.
Reference uredi
- ↑ Braun, A.G., Radman, M. and Grossman, L. (1976). „Enzymic repair of DNA: sites of hydrolysis by the Escherichia coli endonuclease specific for pyrimidine dimers (corendonuclease II)”. Biochemistry 15: 4116-4120. PMID 786366.
- ↑ Riazuddin, S. and Grossman, L. (1977). „Micrococcus luteus correndonucleases. II. Mechanism of action of two endonucleases specific for DNA containing pyrimidine dimers”. J. Biol. Chem. 252: 6287-6293. PMID 330526.
Literatura uredi
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.