Streptogrizin B
Streptogrizin B (EC 3.4.21.81, Streptomyces griseus proteaza B, pronaza B, serinska proteinaza B, Streptomyces griseus proteinaza B, Streptomyces griseus proteinaza 1, Streptomyces griseus serinska proteinaza B) je enzim.[1][2][3][4][5] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Streptogrizin B | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 3.4.21.81 | ||||||||
| CAS broj | 55071-87-9 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- hidroliza proteina sa specifičnošću koja je slična tripsinu
Ovaj enzim je izolovan iz bakterije Streptomyces griseus.
Reference
uredi- ↑ Jurasek, L., Fackre, D. and Smillie, L.B. (1969). „Remarkable homology about the disulfide bridges of a trypsin-like enzyme from Streptomyces griseus”. Biochem. Biophys. Res. Commun. 37: 99-105. PMID 4899581.
- ↑ Fujinaga, M., Read, R.J., Sielecki, A., Ardelt, W., Laskowski, M., Jr. and James, M.N.G. (1982). „Refined crystal structure of the molecular complex of Streptomyces griseus protease B, a serine protease, with the third domain of the ovomucoid inhibitor from turkey”. Proc. Natl Acad. Sci. USA 79: 4868-4872. PMID 6750612.
- ↑ Read, R.J., Fujinaga, M., Sielecki, A.R. and James, M.N.G. (1983). „Structure of the complex of Streptomyces griseus protease B and the third domain of turkey ovomucoid inhibitor at 1.8-Å resolution”. Biochemistry 22: 4420-4433. PMID 6414511.
- ↑ Henderson, G., Krygsman, P., Liu, C.J., Davey, C.C. and Malek, L.T. (1987). „Characterization and structure of genes for proteases A and B from Streptomyces griseus”. J. Bacteriol. 169: 3778-3784. PMID 3112129.
- ↑ Greenblatt, H.M., Ryan, C.A. and James, M.N.G. (1989). „Structure of the complex of Streptomyces griseus proteinase B and polypeptide chymotrypsin inhibitor-1 from Russet Burbank potato tubers at 2.1 Å resolution”. J. Mol. Biol. 205: 201-228. PMID 2494344.
Literatura
uredi- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.