Steril-sulfataza
Steril-sulfataza (EC 3.1.6.2, steroidna sulfataza, sterol sulfataza, dehidroepiandrosteron sulfatna sulfataza, arilsulfataza C, steroidna 3-sulfataza, steroid sulfatna sulfohidrolaza, dehidroepiandrosteronska sulfataza, pregnenolonska sulfataza, fenolna steroidna sulfataza, 3-beta-hidroksisteroid sulfatna sulfataza) je enzim sa sistematskim imenom steril-sulfat sulfohidrolaza.[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Steril-sulfataza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 3.1.6.2 | ||||||||
| CAS broj | 9025-62-1 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- 3beta-hidroksiandrost-5-en-17-on 3-sulfat + H2O 3beta-hidroksiandrost-5-en-17-on + sulfat
Ova enzim takođe deluje na srodne steril sulfate.
Reference
uredi- ↑ Roy, A.B. (1954). „The steroid sulphatase of Patella vlugata”. Biochim. Biophys. Acta 15: 300-301. PMID 13208702.
- ↑ Roy, A.B. (1960). „The synthesis and hydrolysis of sulfate esters”. Adv. Enzymol. Relat. Subj. Biochem. 22: 205-235. PMID 13744184.
- ↑ Stitch, S.R., Halkerston, I.D.K. and Hillman, J. (1965). „The enzymic hydrolysis of steroid conjugates. 1. Sulphatase and β-glucuronidase activity of molluscan extracts”. Biochem. J. 63: 705-710. PMID 13355874.
Literatura
uredi- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.