Stafopain
Stafopain (EC 3.4.22.48, stafilopain) je enzim.[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Stafopain | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 3.4.22.48 | ||||||||
| CAS broj | 347841-89-8 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- Široko endopeptidazno dejstvo na proteinima uključujući elastin, sa veoma ograničenom hidrolizom malih molekula.
Ovaj enzim je prisutan u više vrsti bakterije Staphylococcus.
Reference uredi
- ↑ Hofmann, B., Hecht, H.J., Kiess, M. and Schomburg, D. (1993). „Crystal structure of a thiol proteinase from Staphylococcus aureus' V8 in the E-64 inhibitor complex”. Acta Crystallogr. Sect. A (Suppl.) 49: 102-102.
- ↑ Potempa, J., Dubin, A. and Travis, J. (1998). „Staphylopain”. u: Barrett, A.J., Rawlings, N.D. and Woessner, J.F.. Handbook of Proteolytic Enzymes. London: Handbook of Proteolytic Enzymes. str. 669-671.
- ↑ Dubin, G., Chmiel, D., Mak, P., Rakwalska, M., Rzychon, M. and Dubin, A. (2001). „Molecular cloning and biochemical characterisation of proteases from Staphylococcus epidermidis”. Biol. Chem. 382: 1575-1582. PMID 11767947.
Literatura uredi
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.
- Potempa, J., Dubin, A. and Travis, J. (1998). „Staphylopain”. u: Barrett, A.J., Rawlings, N.D. and Woessner, J.F.. Handbook of Proteolytic Enzymes. London: Handbook of Proteolytic Enzymes. str. 669-671.