Spermin sintaza
Spermin sintaza (EC 2.5.1.22, spermidinska aminopropiltransferaza, sperminska sintetaza) je enzim sa sistematskim imenom S-adenozilmetioninamin:spermidin 3-aminopropiltransferaza.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Spermin sintaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 2.5.1.22 | ||||||||
| CAS broj | 74812-43-4 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
Ovaj enzim nije identičan sa EC 2.5.1.16 (spermidinskom sintazom) ili EC 2.5.1.23 (sim-nespermidinskom sintazom).
Reference
uredi- ↑ Hibasami, H., Borchardt, R.T., Chen, S.-Y., Coward, J.K. and Pegg, A.E. (1980). „Studies of inhibition of rat spermidine synthase and spermine synthase”. Biochem. J. 187: 419-428. PMID 7396856.
- ↑ Pajula, R.-L., Raina, A. and Eloranta, T. (1979). „Polyamine synthesis in mammalian tissues. Isolation and characterization of spermine synthase from bovine brain”. Eur. J. Biochem. 101: 619-626. PMID 520313.
Literatura
uredi- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.