Fas-aktivirana serin/treonin kinaza
(Preusmjereno sa stranice STK10)
Fas-aktivirana serin/treonin kinaza (EC 2.7.11.8, FAST, FASTK, STK10) je enzim sa sistematskim imenom ATP:(Fas-aktivirani serin/treonin protein) fosfotransferaza.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Fas-aktivirana serin/treonin kinaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 2.7.11.8 | ||||||||
| CAS broj | 170347-50-9 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
Ovaj enzim se aktivira tokom Fas-posredovane apoptoze.
Reference
uredi- ↑ Tian, Q., Taupin, J., Elledge, S., Robertson, M. and Anderson, P. (1995). „Fas-activated serine/threonine kinase (FAST) phosphorylates TIA-1 during Fas-mediated apoptosis”. J. Exp. Med. 182: 865-874. PMID 7544399.
- ↑ Li, W., Simarro, M., Kedersha, N. and Anderson, P. (2004). „FAST is a survival protein that senses mitochondrial stress and modulates TIA-1-regulated changes in protein expression”. Mol. Cell. Biol. 24: 10718-10732. PMID 15572676.
Literatura
uredi- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.