Sve-trans-nonaprenil difosfat sintaza (geranilgeranil-difosfat specifična)
(Preusmjereno sa stranice SPS2)
Sve-trans-nonaprenil difosfat sintaza (geranilgeranil-difosfat specifična) (EC 2.5.1.85, nonaprenil difosfatna sintaza, solanezil difosfatna sintaza, At-SPS2, At-SPS1, SPS1, SPS2) je enzim sa sistematskim imenom geranilgeranil-difosfat:izopentenil-difosfat transtransferaza (dodaje 5 izopentenilnih jedinica).[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Sve-trans-nonaprenil difosfat sintaza (geranilgeranil-difosfat specifična) | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 2.5.1.85 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- geranilgeranil difosfat + 5 izopentenil difosfat 5 difosfat + sve-trans-nonaprenil difosfat
Geranilgeranil difosfat je preferentni supstrat.
Reference uredi
- ↑ Hirooka, K., Bamba, T., Fukusaki, E. and Kobayashi, A. (2003). „Cloning and kinetic characterization of Arabidopsis thaliana solanesyl diphosphate synthase”. Biochem. J. 370: 679-686. PMID 12437513.
- ↑ Hirooka, K., Izumi, Y., An, C.I., Nakazawa, Y., Fukusaki, E. and Kobayashi, A. (2005). „Functional analysis of two solanesyl diphosphate synthases from Arabidopsis thaliana”. Biosci. Biotechnol. Biochem. 69: 592-601. PMID 15784989.
- ↑ Jun, L., Saiki, R., Tatsumi, K., Nakagawa, T. and Kawamukai, M. (2004). „Identification and subcellular localization of two solanesyl diphosphate synthases from Arabidopsis thaliana”. Plant Cell Physiol. 45: 1882-1888. PMID 15653808.
Literatura uredi
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.