Streptomicin 6-kinaza
(Preusmjereno sa stranice SM 6-kinaza)
Streptomicin 6-kinaza (EC 2.7.1.72, streptidinska kinaza, SM 6-kinaza, streptomicinska 6-kinaza (fosforilacija), streptidinska kinaza (fosforilacija), streptomicinska 6-O-fosfotransferaza, streptomicinska 6-fosfotransferaza) je enzim sa sistematskim imenom ATP:streptomicin 6-fosfotransferaza.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Streptomicin 6-kinaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 2.7.1.72 | ||||||||
| CAS broj | 37278-11-8 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- ATP + streptomicin ADP + streptomicin 6-fosfat
dATP može da zameni ATP.
Reference uredi
- ↑ Walker, J.B. and Skorvaga, M. (1973). „Phosphorylation of streptomycin and dihydrostreptomycin by Streptomyces. Enzymatic synthesis of different diphosphorylated derivatives”. J. Biol. Chem. 248: 2435-2440. PMID 4121456.
- ↑ Walker, J.B. and Walker, M.S. (1967). „Streptomycin biosynthesis. Enzymatic synthesis of O-phosphorylstreptidine from streptidine and adenosinetriphosphate”. Biochim. Biophys. Acta 148: 335-341. PMID 6075410.
Literatura uredi
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.