2,4,7-trihidroksi-1,4-benzoksazin-3-on-glukozid 7-O-metiltransferaza
2,4,7-Trihidroksi-1,4-benzoksazin-3-on-glukozid 7-O-metiltransferaza (EC 2.1.1.241, BX7 (gen), OMT BX7) je enzim sa sistematskim imenom S-adenozil-L-metionin:(2R)-4,7-dihidroksi-3-okso-3,4-dihidro-2H-1,4-benzoksazin-2-il beta-D-glukopiranozid 7-O-metiltransferaza.[1] Ovaj enzim katalizuje sledeću hemijsku reakciju
| 2,4,7-Trihidroksi-1,4-benzoksazin-3-on-glukozid 7-O-metiltransferaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 2.1.1.241 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- S-adenozil-L-metionin + (2R)-4,7-dihidroksi-3-okso-3,4-dihidro-2H-1,4-benzoksazin-2-il beta-D-glukopiranozid S-adenozil-L-homocistein + (2R)-4-hidroksi-7-metoksi-3-okso-3,4-dihidro-2H-1,4-benzoksazin-2-il beta-D-glukopiranozid
Ovaj enzim učestvuje u biosintezi zaštitnog benzoksazinoida DIMBOA [(2R)-4-hidroksi-7-metoksi-3-okso-3,4-dihidro-2H-1,4-benzoksazina] kod pojedinih biljki, najčešće iz familije Poaceae (trave).
Reference
uredi- ↑ Jonczyk, R., Schmidt, H., Osterrieder, A., Fiesselmann, A., Schullehner, K., Haslbeck, M., Sicker, D., Hofmann, D., Yalpani, N., Simmons, C., Frey, M. and Gierl, A. (2008). „Elucidation of the final reactions of DIMBOA-glucoside biosynthesis in maize: characterization of Bx6 and Bx7”. Plant Physiol. 146: 1053-1063. PMID 18192444.
Literatura
uredi- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.